203787-17-1Relevant articles and documents
Synthesis of ellipticine by hetaryne cycloadditions - Control of regioselectivity
Díaz, Maite,Cobas, Agustín,Guitián, Enrique,Castedo, Luis
, p. 4543 - 4549 (2007/10/03)
We have modified Gribble's and Moody's approaches to ellipticines by introducing substituents into the 3,4-didehydropyridine dienophile to control the key cycloaddition step. A chloro substituent at position 2 improved the yields and the regioselectivities of the cycloadditions and the overall efficiency of the synthesis of ellipticine.