203940-17-4

Basic information

• Product Name: methyl 3-[(E)-2-(7-chloro-2-quinolyl)vinyl]benzoate
• Synonyms: methyl 3-[(E)-2-(7-chloro-2-quinolyl)vinyl]benzoate
• CAS NO: 203940-17-4
• Molecular Weight: 323.779
• Mol File: 203940-17-4.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: methyl 3-[(E)-2-(7-chloro-2-quinolyl)vinyl]benzoate(CAS DataBase Reference)
• NIST Chemistry Reference: methyl 3-[(E)-2-(7-chloro-2-quinolyl)vinyl]benzoate(203940-17-4)
• EPA Substance Registry System: methyl 3-[(E)-2-(7-chloro-2-quinolyl)vinyl]benzoate(203940-17-4)

Safety Data

• Hazardous Substances Data: 203940-17-4(Hazardous Substances Data)

Upstream product

• 4965-33-7 2-methyl-7-chloroquinoline 
• 52178-50-4 Methyl 3-formylbenzoate 

Downstream Products

• 904916-27-4 {1-[1-{3-[(E)-2-(7-Chloro-quinolin-2-yl)-vinyl]-phenyl}-2-(1,3-dioxo-1,3-dihydro-isoindol-2-yl)-ethylsulfanylmethyl]-cyclopropyl}-acetic acid benzyl ester 
• 904916-32-1 [1-(2-(4-Chloro-benzenesulfonylamino)-1-{3-[(E)-2-(7-chloro-quinolin-2-yl)-vinyl]-phenyl}-ethylsulfanylmethyl)-cyclopropyl]-acetic acid benzyl ester 
• 904916-33-2 (+/-)-methyl 4-{[(2-{4-chlorophenylsulfonylamino}-1-{3-[(E)-2-(7-chloro-2-quinolyl)vinyl]phenyl}ethyl)thio]methyl}phenylacetate 
• 904916-34-3 (+/-)-methyl 4-{[(2-{4-chlorophenylsulfonylamino}-1-{3-[(E)-2-(7-chloro-2-quinolyl)vinyl]phenyl}ethyl)thio]-2-ethyl}benzoate 
• 904916-37-6 (+/-)-methyl 4-{[(2-{4-nitrophenylsulfonylamino}-1-{3-[(E)-2-(7-chloro-2-quinolyl)vinyl]phenyl}ethyl)thio]methyl}benzoate 
• 904916-29-6 (+/-)-methyl 4-{[(1-{3-[(E)-2-(7-chloro-2-quinolyl)vinyl]phenyl}-2-phthalimidoethyl)thio]-2-ethyl}benzoate 
• 904916-28-5 (+/-)-methyl 4-{[(1-{3-[(E)-2-(7-chloro-2-quinolyl)vinyl]phenyl}-2-phthalimidoethyl)thio]methyl}phenylacetate 
• 904916-38-7 (+/-)-methyl 4-{[(2-{4-fluorophenylsulfonylamino}-1-{3-[(E)-2-(7-chloro-2-quinolyl)vinyl]phenyl}ethyl)thio]methyl}benzoate 
• 203940-24-3 (+/-)-methyl 4-{[(1-{3-[(E)-2-(7-chloro-2-quinolyl)vinyl]phenyl}-2-phthalimidoethyl)thio]methyl}benzoate 
• 203940-25-4 (+/-)-methyl 4-{[(2-{4-chlorophenylsulfonylamino}-1-{3-[(E)-2-(7-chloro-2-quinolyl)vinyl]phenyl}ethyl)thio]methyl}benzoate 
• 904916-36-5 (+/-)-methyl 4-{[(2-{4-bromophenylsulfonylamino}-1-{3-[(E)-2-(7-chloro-2-quinolyl)vinyl]phenyl}ethyl)thio]methyl}benzoate 
• 904916-31-0 (+/-)-methyl 4-[(2-{4-chlorophenylsulfonylamino}-1-{3-[(E)-2-(7-chloro-2-quinolyl)vinyl]phenyl}ethyl)thio]-3,3-dimethylbutyrate 
• 904916-35-4 (+/-)-methyl 4-{[(2-{phenylsulfonylamino}-1-{3-[(E)-2-(7-chloro-2-quinolyl)vinyl]phenyl}ethyl)thio]methyl}benzoate 

Relevant articles and documents

PROCESS FOR AND INTERMEDIATES OF LEUKOTRIENE ANTAGONISTS

A process for synthesizing a β- ketoester of formula (VII) which comprises: (a) converting 3-methylbenzoic acid into alkyl 3-methylbenzoate; (b) reacting 3 -methyl benzoate to form alkyl 3 -bromomethylbenzoate; (c)converting alkyl 3-bromo methyl benzoate into alkyl 3-formylbenzoate; (d) condensing alkyl 3-formyl benzoate with 7- Chioroquinaldine to give alkyl 3- [((7-Chloro-2-quinolinyl) ethenyl)]benzoate; (e) hydrolyzing alkyl 3 -[((7-Chloro-2-quinolinyl)ethenyl) benzoate to give 3-[((7- Chloro- 2-quinolinyl)ethenyl)]benzoic acid; and (f) reacting 3-[((7-Chloro-2-quinolinyI) ethenyjbenzoic acid with a malonate to obtain a compound of structural formula VII.