20414-93-1

Basic information

• Product Name: E-methyl-2-phenyl-5-pentadien-2,4-oate de methyle
• CAS NO: 20414-93-1
• Molecular Weight: 202.253
• Mol File: 20414-93-1.mol
• Article Data: 6

Chemical Properties

• CAS DataBase Reference: E-methyl-2-phenyl-5-pentadien-2,4-oate de methyle(CAS DataBase Reference)
• NIST Chemistry Reference: E-methyl-2-phenyl-5-pentadien-2,4-oate de methyle(20414-93-1)
• EPA Substance Registry System: E-methyl-2-phenyl-5-pentadien-2,4-oate de methyle(20414-93-1)

Safety Data

• Hazardous Substances Data: 20414-93-1(Hazardous Substances Data)

Upstream product

• 104-55-2 3-phenyl-propenal 
• 103-26-4 methyl cinnamate 
• 29668-62-0 methyl 2-(diethoxyphosphoryl)propanoate 
• 100-52-7 benzaldehyde 
• 104-54-1 3-Phenylpropenol 
• 1367876-33-2 [(2Z,4E)-2-methoxycarbonyl-5-phenyl-2,4-pentadienyl]triphenylphosphonium bromide 
• 918155-94-9 methyl (2Z,4E)-2-(bromomethyl)-5-phenylpenta-2,4-dienoate 
• 89812-55-5 (E)-2-Methyl-1,1-bis-methylsulfanyl-5-phenyl-penta-1,4-dien-3-one 
• 129611-81-0 5,5-bis(methylthio)-4-methyl-2,4-pentadienal 
• 15081-13-7 3-methyl-4,4-bis-methylsulfanyl-but-3-en-2-ol 
• 17649-87-5 3-methyl-4,4-bis(methylthio)but-3-en-2-one 
• 74-88-4 methyl iodide 
• 67-56-1 methanol 
• 14371-10-9 (E)-3-phenylpropenal 

Downstream Products

• 20414-94-2 (2E,4E)-2-methyl-5-phenyl-2,4-pentadienoic acid 

Relevant articles and documents

Highly Regio- A nd Enantioselective Hydrogenation of Conjugated α-Substituted Dienoic Acids

Highly regio- A nd enantioselective hydrogenation of conjugated α-substituted dienoic acids was realized for the first time using Trifer-Rh complex, providing a straightforward method for the synthesis of chiral α-substituted ?,?′-unsaturated acids. DFT calculations revealed N+H-O hydrogen bonding interaction is formed to stabilize the transition state and the coordination of 4,5-double bond to Rh(III) center would facilitate the reductive elimination process. This hydrogenation provided a gram-scale synthesis of the precursor of sacubitril.

A new 1,5- to 1,11-carbonyl transposition protocol involving ketene dithioacetal chemistry: An efficient polyene synthesis

An efficient strategy for alternative 1,5-, 1,7-, 1,9- and 1,11- carbonyl transposition has been developed via 1,2-reductive or alkylative addition to 5,5-bis(methylthio)-2,4-pentadienals 3a-b, 7,7-bis(methylthio)-2,4,6-heptatrienones 5,9,9-bis(methylthio)-2,4,6,8-nonatetraenones 8 and 11,11-bis(methylthio)-2,4,6,8,10-undecapentaenones 11 followed by BF3,Et2O induced methanolysis of the resulting carbinols to the corresponding polyene esters. The synthesis of the novel polyene aldehydes 3a-b, 7a-b, 10b and polyenones 5, 8, 11 precursors has also been described following iterative Vielsmeier-Haack reaction and aldol condensation.

A Novel General Method for the Synthesis of 2-Methyl-Substituted and 2-Unsubstituted Methyl 5-Aryl-2,4-pentadienoates

-