204194-28-5Relevant articles and documents
Practical synthesis of the rebeccamycin aglycone and related analogs by oxidative cyclization of bisindolylmaleimides with a Wacker-type catalytic system
Wang, Jianji,Rosingana, Miguel,Watson, Daniel J.,Dowdy, Eric D.,Discordia, Robert P.,Soundarajan, Nachimuthu,Li, Wen-Sen
, p. 8935 - 8937 (2007/10/03)
Using atmospheric O2 as the stoichiometric oxidant, Pd2+/Cu2+-catalyzed oxidative cyclization of the corresponding bisindolylmaleimides provides the rebeccamycin aglycone and related indolo[2,3-a]pyrrolo[3,4-c]carbazoles in 58-88% yield. The method is operationally simple and utilizes readily prepared substrates, making the process amenable to scaleup.