204323-40-0

Basic information

• Product Name: (R)-2-Fluoro-N-((1S,2S)-2-hydroxy-1-methyl-2-phenyl-ethyl)-N-methyl-butyramide
• Synonyms: (R)-2-Fluoro-N-((1S,2S)-2-hydroxy-1-methyl-2-phenyl-ethyl)-N-methyl-butyramide
• CAS NO: 204323-40-0
• Molecular Weight: 253.317
• Mol File: 204323-40-0.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: (R)-2-Fluoro-N-((1S,2S)-2-hydroxy-1-methyl-2-phenyl-ethyl)-N-methyl-butyramide(CAS DataBase Reference)
• NIST Chemistry Reference: (R)-2-Fluoro-N-((1S,2S)-2-hydroxy-1-methyl-2-phenyl-ethyl)-N-methyl-butyramide(204323-40-0)
• EPA Substance Registry System: (R)-2-Fluoro-N-((1S,2S)-2-hydroxy-1-methyl-2-phenyl-ethyl)-N-methyl-butyramide(204323-40-0)

Safety Data

• Hazardous Substances Data: 204323-40-0(Hazardous Substances Data)

Upstream product

• 75-03-6 ethyl iodide 
• 204323-36-4 (1S,2S)-pseudoephedrine α-fluoroacetamide 
• 425-75-2 trifluoromethanesulfonic acid ethyl ester 

Relevant articles and documents

Practical methodology for the asymmetric synthesis of organofluorine compounds

Pseudoephedrine α-fluoroacetamide (1), a nonvolatile, crystalline solid, is alkylated efficiently and with high diastereoselectivity with reactive alkyl halides. The alkylation products can be hydrolyzed under mild basic conditions to form α-fluoro carboxylates with high enantiomeric enrichment.