204395-52-8

Basic information

• Product Name: CLOZAPINE (D4)
• Synonyms: CLOZAPINE (D4);Clozapine-D4 solution
• CAS NO: 204395-52-8
• Molecular Formula: C18H15ClD4N4
• Molecular Weight: 330.85
• EINECS: 200-659-6
• Mol File: 204395-52-8.mol
• Article Data: 0

Chemical Properties

• Flash Point: 9℃
• Appearance: /
• Storage Temp.: ?20°C
• CAS DataBase Reference: CLOZAPINE (D4)(CAS DataBase Reference)
• NIST Chemistry Reference: CLOZAPINE (D4)(204395-52-8)
• EPA Substance Registry System: CLOZAPINE (D4)(204395-52-8)

Safety Data

• Hazard Codes: F,T
• Statements: 11-23/24/25-39/23/24/25
• Safety Statements: 7-16-36/37-45
• RIDADR: UN1230 - class 3 - PG 2 - Methanol, solution
• WGK Germany: 1
• Hazardous Substances Data: 204395-52-8(Hazardous Substances Data)

Usage

Description

Clozapine (d4), also known as Clozapine-D4, is a stable-labeled internal standard used for the quantitation of Clozapine levels in biological samples such as urine, serum, or plasma. It plays a crucial role in clinical toxicology, forensic analysis, and urine drug testing applications. Clozapine itself, sold under the brand names Clozaril and FazaClo in the US, is an atypical antipsychotic drug primarily used for the treatment of schizophrenia.

Uses

Used in Clinical Toxicology:
Clozapine (d4) is used as a quantitation standard for determining Clozapine levels in biological samples. This helps in assessing the safety and efficacy of Clozapine therapy, as well as monitoring patients for potential drug interactions or overdose situations.
Used in Forensic Analysis:
In forensic analysis, Clozapine (d4) serves as a reference material for the accurate measurement of Clozapine concentrations in samples. This aids in investigations involving drug-related crimes or cases where the presence of Clozapine may be relevant to the outcome.
Used in Urine Drug Testing Applications:
Clozapine (d4) is utilized as an internal standard in urine drug testing to ensure the accuracy and reliability of test results. This is particularly important for monitoring patients undergoing Clozapine treatment, as well as for detecting the abuse or misuse of the drug.
Used in Pharmaceutical Industry:
Clozapine (d4) is used as a quality control standard in the development, manufacturing, and quality assurance processes of Clozapine-containing pharmaceutical products. This ensures that the final product meets the required specifications and maintains a consistent level of therapeutic efficacy.
Used in Research and Development:
In the field of research and development, Clozapine (d4) is employed as a tool for studying the pharmacokinetics, pharmacodynamics, and potential interactions of Clozapine with other drugs. This contributes to a better understanding of the drug's mechanism of action and helps in the development of new therapeutic strategies for schizophrenia and other related conditions.