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204452-90-4

204452-90-4

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204452-90-4 Usage

General Description

2-DIMETHOXYMETHYL-[1,8]NAPHTHYRIDINE is a chemical compound with the formula C13H13NO2. It is a naphthyridine derivative with two methoxy groups attached to the methyl group at the 2-position. 2-DIMETHOXYMETHYL-[1,8]NAPHTHYRIDINE has been studied for its potential pharmaceutical applications, particularly as a DNA-binding agent with potential antitumor and antibacterial properties. Research has shown that 2-DIMETHOXYMETHYL-[1,8]NAPHTHYRIDINE exhibits strong binding affinity to DNA, making it a promising candidate for further investigation as an anti-cancer and antimicrobial agent. Additionally, this compound is also of interest in the field of medicinal chemistry for the development of novel drugs and therapies.

Check Digit Verification of cas no

The CAS Registry Mumber 204452-90-4 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 2,0,4,4,5 and 2 respectively; the second part has 2 digits, 9 and 0 respectively.
Calculate Digit Verification of CAS Registry Number 204452-90:
(8*2)+(7*0)+(6*4)+(5*4)+(4*5)+(3*2)+(2*9)+(1*0)=104
104 % 10 = 4
So 204452-90-4 is a valid CAS Registry Number.
InChI:InChI=1/C11H12N2O2/c1-14-11(15-2)9-6-5-8-4-3-7-12-10(8)13-9/h3-7,11H,1-2H3

204452-90-4 Well-known Company Product Price

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  • Aldrich

  • (ADE000834)  2-Dimethoxymethyl-[1,8]naphthyridine  AldrichCPR

  • 204452-90-4

  • ADE000834-1G

  • 1,930.50CNY

  • Detail

204452-90-4SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 11, 2017

Revision Date: Aug 11, 2017

1.Identification

1.1 GHS Product identifier

Product name 2-Dimethoxymethyl-[1,8]naphthyridine

1.2 Other means of identification

Product number -
Other names 2-(dimethoxymethyl)-1,8-naphthyridine

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:204452-90-4 SDS

204452-90-4Downstream Products

204452-90-4Relevant articles and documents

Design, Synthesis, and Biological Evaluation of 2-Formyl Tetrahydronaphthyridine Urea Derivatives as New Selective Covalently Reversible FGFR4 Inhibitors

Chen, Hao,Ding, Ke,Huang, Jing,Li, Jie,Peng, Lijie,Tu, Zheng-Chao,Zhang, Zhang,Zhang, Zhen,Zhou, Yang

supporting information, p. 3249 - 3265 (2022/02/16)

Aberrant FGF19/FGFR4 signaling is an oncogenic driver force for the development of human hepatocellular carcinoma (HCC). A series of 2-formyl tetrahydronaphthyridine urea derivatives were designed and synthesized as new covalently reversible inhibitors of

Characterization of an aromatic trifluoromethyl ketone as a new warhead for covalently reversible kinase inhibitor design

Zhang, Zhen,Wang, Yongjin,Chen, Xiaojuan,Song, Xiaojuan,Tu, Zhengchao,Chen, Yongheng,Zhang, Zhimin,Ding, Ke

supporting information, (2021/10/21)

An aromatic trifluoromethyl ketone moiety was characterized as a new warhead for covalently reversible kinase inhibitor design to target the non-catalytic cysteine residue. Potent and selective covalently reversible inhibitors of FGFR4 kinase were success

FGFR4 INHIBITOR, PREPARATION METHOD THEREFOR, AND APPLICATIONS THEREOF

-

Paragraph 0159; 0160, (2019/02/28)

The present invention relates to an FGFR4 inhibitor having a structure represented by formula (I), preparation method therefor, and applications thereof. A series of compounds represented by formula (I) in the present invention have a very-strong inhibiti

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