2045-76-3Relevant articles and documents
SYNTHESIS OF SOME SUBSTITUTED PYRROLINE-1-OXIDES BY CATALYTIC HYDROGENATION OF ALIPHATIC GAMMA-NITROVCARBONYL COMPOUNDS
Turner, Marvin J.,Luckenbach, Lee A.,Turner, Elizabeth L.
, p. 1377 - 1386 (2007/10/02)
Various pyrroline-1-oxides were prepared by the catalytic hydrogenation of appropriately substituted gamma-nitrocarbonyl compounds.Initially the reaction affords a mixture of the nitrone and the corresponding hydroxilamine, but copper(II)-catalyzed aerial oxidation readily converts the hydroxylamine to the desired cyclic nitrone.This method was found to be more convenient than the zinc-ammonium chloride reduction and the corresponding yields were comparable.