204505-16-8

Basic information

• Product Name: 3-{2-[1-Methoxy-meth-(Z)-ylidene]-cyclohexyl}-propionic acid methyl ester
• Synonyms: 3-{2-[1-Methoxy-meth-(Z)-ylidene]-cyclohexyl}-propionic acid methyl ester
• CAS NO: 204505-16-8
• Molecular Weight: 212.289
• Mol File: 204505-16-8.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: 3-{2-[1-Methoxy-meth-(Z)-ylidene]-cyclohexyl}-propionic acid methyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: 3-{2-[1-Methoxy-meth-(Z)-ylidene]-cyclohexyl}-propionic acid methyl ester(204505-16-8)
• EPA Substance Registry System: 3-{2-[1-Methoxy-meth-(Z)-ylidene]-cyclohexyl}-propionic acid methyl ester(204505-16-8)

Safety Data

• Hazardous Substances Data: 204505-16-8(Hazardous Substances Data)

Upstream product

• 10407-33-7 methyl 3-(2-oxocyclohexyl)propionate 
• 4009-98-7 (methoxymethyl)triphenylphosphonium chloride 
• 1125-99-1 1-(1-Cyclohexen-1-yl)pyrrolidine 
• 108-94-1 cyclohexanone 

Downstream Products

• 288571-68-6 1-Benzenesulfonyl-4-{2-[1-methoxy-meth-(E)-ylidene]-cyclohexyl}-butan-2-one 
• 288571-52-8 4-{2-[1-Methoxy-meth-(E)-ylidene]-cyclohexyl}-1-(2-methyl-propane-2-sulfonyl)-butan-2-one 
• 204505-17-9 1-(4-Chloro-phenyl)-3-{2-[1-methoxy-meth-(Z)-ylidene]-cyclohexyl}-propan-1-one 

Relevant articles and documents

Antimalarial sulfide, sulfone, and sulfonamide trioxanes

A series of trioxanes featuring sulfide, sulfone, and sulfonamide substituents in diverse positions has been prepared. Structure-activity relationship (SAR) generalizations highlight two major factors controlling the antimalarial potency of these new chemical entities: (1) the proximity of the sulfur-containing substituent to the crucial peroxide bond and (2) the oxidation state of the sulfur-containing substituent. Generally, sulfones are more antimalarially potent than the corresponding sulfides. Copyright (C) 2000 Elsevier Science Ltd.