204511-51-3Relevant articles and documents
New 2-arylpyrazolo[3,4-c]quinoline derivatives as potent and selective human A3 adenosine receptor antagonists. Synthesis, pharmacological evaluation, and ligand-receptor modeling studies
Colotta, Vittoria,Catarzi, Daniela,Varano, Flavia,Capelli, Francesca,Lenzi, Ombretta,Filacchioni, Guido,Martini, Claudia,Trincavelli, Letizia,Ciampi, Osele,Pugliese, Anna Maria,Pedata, Felicita,Schiesaro, Andrea,Morizzo, Erika,Moro, Stefano
, p. 4061 - 4074 (2008/02/12)
This paper reports the study of some 2-arylpyrazolo[3,4-c]quinolin-4-ones, 4-amines, and 4-amino-substituted derivatives designed as human A3 adenosine receptor (AR) antagonists. Most of the herein reported compounds showed a nanomolar affinity