204926-49-8 Usage
Description
d,l-trans-3-bromo-4-hydroxytetrahydrofuran is a synthetic chemical compound with the molecular formula C4H7BrO2. It is a derivative of tetrahydrofuran, featuring a bromine and a hydroxyl group in its structure. This stereochemically pure compound is distinguished by its trans configuration, which significantly influences its chemical properties.
Uses
Used in Pharmaceutical and Agrochemical Industries:
d,l-trans-3-bromo-4-hydroxytetrahydrofuran is utilized as an intermediate in the synthesis of various pharmaceuticals and agrochemicals. Its unique structure and functional groups make it a valuable component in the development of new drugs and agricultural products.
Used in Fine Chemical Production:
d,l-trans-3-bromo-4-hydroxytetrahydrofuran is also employed in the production of a range of fine chemicals, where its specific properties can be leveraged to create high-quality specialty products.
Used as a Reagent in Organic Synthesis:
d,l-trans-3-bromo-4-hydroxytetrahydrofuran serves as a reagent in organic synthesis, facilitating various chemical reactions and contributing to the formation of desired products.
Used in Medicinal Chemistry and Drug Development:
With its potential applications in medicinal chemistry, d,l-trans-3-bromo-4-hydroxytetrahydrofuran is explored for its role in drug development, where it may contribute to the discovery of novel therapeutic agents.
Check Digit Verification of cas no
The CAS Registry Mumber 204926-49-8 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 2,0,4,9,2 and 6 respectively; the second part has 2 digits, 4 and 9 respectively.
Calculate Digit Verification of CAS Registry Number 204926-49:
(8*2)+(7*0)+(6*4)+(5*9)+(4*2)+(3*6)+(2*4)+(1*9)=128
128 % 10 = 8
So 204926-49-8 is a valid CAS Registry Number.
204926-49-8Relevant articles and documents
Regiospecific Vinyl Phosphate/β-Keto Phosphonate Rearrangements Initiated by Halogen-Metal Exchange
Baker, Tracy J.,Wiemer, David F.
, p. 2613 - 2618 (2007/10/03)
A new strategy has been developed for preparation of β-keto phosphonates via a halogen-metal exchange induced 1,3-phosphorus migration of 2-bromovinyl phosphates. These intermediates can be prepared through conversion of an α-bromo ketone to the appropriate enolate by reaction with strong base, or through conjugate addition to an α-bromo α,β-unsaturated ketone. In either case, trapping the resulting enolate by reaction with a dialkyl phosphorochloridate gives the 2-bromovinyl phosphate. Metalation can be accomplished upon treatment with n-BuLi, and rearrangement is facile once metalation has been achieved. Studies with isotopically labeled substrates have shown that this rearrangement is regiospecific, in contrast to vinyl phosphate/β-keto phosphonate rearrangements induced by strong base where regioisomeric products are sometimes obtained.
