20503-92-8

Basic information

• Product Name: 3-Phenyloxazolidine
• Synonyms: 3-Phenyloxazolidine
• CAS NO: 20503-92-8
• Molecular Formula: C₉H₁₁NO
• Molecular Weight: 149.19
• Mol File: 20503-92-8.mol
• Article Data: 7

Chemical Properties

• Melting Point: 28 °C
• Boiling Point: 94 °C(Press: 1.5 Torr)
• Appearance: /
• Density: 1.1056 g/cm3(Temp: 30 °C)
• PKA: 4.16±0.40(Predicted)
• CAS DataBase Reference: 3-Phenyloxazolidine(CAS DataBase Reference)
• NIST Chemistry Reference: 3-Phenyloxazolidine(20503-92-8)
• EPA Substance Registry System: 3-Phenyloxazolidine(20503-92-8)

Safety Data

• Hazardous Substances Data: 20503-92-8(Hazardous Substances Data)

Upstream product

• 80-15-9 Cumene hydroperoxide 
• 121-69-7 N,N-dimethyl-aniline 
• 7647-01-0 hydrogenchloride 
• 50-00-0 formaldehyd 
• 16285-78-2 2,3-Diphenyl-1,3-oxazolidine 
• 71-43-2 benzene 
• 84877-51-0 N-phenyloxazolidine-2,-d2 
• 115011-74-0 N-phenyloxazolidin-5-one 
• 103-01-5 N-Phenylglycine 
• 84877-55-4 2-(methylphenylamino)ethyl tert-butyl peroxide 
• 122-98-5 2-Anilinoethanol 
• 591-50-4 iodobenzene 

Downstream Products

• 20503-91-7 3,3'-(4,4'-methanediyl-diphenyl)-bis-oxazolidine 
• 13887-35-9 4-{3-[N-(2-hydroxy-ethyl)-anilino]-2,2-dimethyl-propionyl}-morpholine 
• 108975-44-6 4-{[N-(2-hydroxy-ethyl)-anilino]-methyl}-2,6-dimethyl-phenol 
• 108923-46-2 2-(N-but-2-enyl-anilino)-ethanol 
• 108971-56-8 2-[N-(2-hydroxy-ethyl)-anilinomethyl]-4,6-dimethyl-phenol 
• 108519-13-7 2,4,6-tris-{[N-(2-hydroxy-ethyl)-anilino]-methyl}-phenol 
• 5461-49-4 N-ethylformanilide 
• 696-18-4 1-phenylaziridine 
• 1149-23-1 diethyl 2,6-dimethyl-1,4-dihydropyridine-3,5-dicarboxylate 
• 16502-01-5 tetrahydrobetacarboline 
• 103174-73-8 diethyl 2,6-dimethyl-1-phenyl-1,4-dihydropyridine-3,5-dicarboxylate 
• 1968-05-4 3,3'-diindolylmethane 
• 61004-90-8 4-phenyl-octahydro-pyrano[3,2-f][1,4]oxazepine 

Relevant articles and documents

The synthesis of new 1,3-oxazolidines and 1,3-oxazinanes containing (η6-arene)tricarbonylchromium group based on condensation between aldehydes and amino alcohols

The condensation reactions of β- and γ-amino alcohols containing phenyl or (η6-arene) tricarbonylchromium substituent with formaldehyde, acetaldehyde, benzaldehyde, and (η6-benzaldehyde)tricarbonylchromium were studied. The resulting 1,3-oxazolidine and 1,3-oxazinane products were isolated in a pure form and identified by different physicochemical methods. The effect of (η6-arene)tricarbonylchromium moiety on the reaction process was demonstrated.

The functionalisation of electron rich aromatic compounds with 1,3-oxazolidines and 1,3-dimethylimidazolidine

N-Phenyl- and N-alkyl-oxazolidines react with alkyl chlorosilanes in the presence of electron rich aromatic compounds with the formation of the expected Mannich bases: 2-methoxycarbonyl-3-methyloxazolidine also reacts with 2-methylfuran in the presence of thionyl chloride to give an a-amino acid derivative: the iminium salt derived from 1,3-dimethylimidazolidine was also shown to react with 2-methylfuran.

Formation of azomethine ylids by thermolysis of oxazolidines. Study of the reaction in solution and in the gaseous phase

Thermolysis of oxazolidines leads to azomethine ylids via cycloreversion.In the liquid phase, these intermediates then give 1-3 dipolar cycloaddition; in the gaseous phase, they lead to aziridines.With an alkyl group in position 2, we observed also the formation of enamines.The effect of substituents on both the cycloreversion reaction and the evolution of azomethine ylids was studied.The mechanism of the process tautomerism aziridine -> azomethine ylid -> enamine is discussed.Keywords - azomethine ylids / oxazolidines / cycloreversion / aziridines / enamines / tautomerism