205034-11-3

Basic information

• Product Name: Octadecanoic acid 3-formyl-4-nitro-phenyl ester
• CAS NO: 205034-11-3
• Molecular Weight: 433.588
• Mol File: 205034-11-3.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: Octadecanoic acid 3-formyl-4-nitro-phenyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: Octadecanoic acid 3-formyl-4-nitro-phenyl ester(205034-11-3)
• EPA Substance Registry System: Octadecanoic acid 3-formyl-4-nitro-phenyl ester(205034-11-3)

Safety Data

• Hazardous Substances Data: 205034-11-3(Hazardous Substances Data)

Upstream product

• 42454-06-8 2-nitro-5-hydroxybenzaldehyde 
• 638-08-4 stearic anhydride 

Downstream Products

• 205034-16-8 Octadecanoic acid 4-amino-3-[1,3]dioxolan-2-yl-phenyl ester 

Relevant articles and documents

Synthesis of a new class of camptothecin derivatives, the long-chain fatty acid esters of 10-hydroxycamptothecin, as a potent prodrug candidate, and their in vitro metabolic conversion by carboxylesterases

Five (20S)-10-hydroxycamptothecin derivatives carrying the long-chain fatty acid eaters were prepared for the development of a new class of prodrug-type agents. In vitro experiments using three kinds of purified carboxylesterase isozymes from the liver microsomes of rat, pig, and human demonstrated that these derivatives were efficiently metabolized by enzymes compared with CPT-11.