205047-49-0

Basic information

• Product Name: 4-(4-Oxo-azetidin-2-yloxy)-benzoic acid tert-butyl ester
• CAS NO: 205047-49-0
• Molecular Weight: 263.293
• Mol File: 205047-49-0.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 4-(4-Oxo-azetidin-2-yloxy)-benzoic acid tert-butyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: 4-(4-Oxo-azetidin-2-yloxy)-benzoic acid tert-butyl ester(205047-49-0)
• EPA Substance Registry System: 4-(4-Oxo-azetidin-2-yloxy)-benzoic acid tert-butyl ester(205047-49-0)

Safety Data

• Hazardous Substances Data: 205047-49-0(Hazardous Substances Data)

Upstream product

• 28562-53-0 4-acetoxy azetidinone 
• 25804-49-3 tert-butyl 4-hydroxybenzoate 

Downstream Products

• 205047-61-6 4-(4-Oxo-1-phenylcarbamoyl-azetidin-2-yloxy)-benzoic acid tert-butyl ester 

Relevant articles and documents

Design and synthesis of monocyclic β-lactams as mechanism-based inhibitors of human cytomegalovirus protease

Mechanism based inhibitors of HCMV protease have been designed based on the monocyclic β-lactam nucleus, which have been shown to acylate the viral enzyme in a time dependant manner. SAR in a series of monocyclic β-lactam N-ureas, has defined the size and relative stereochemisty of the C-3 substituent producing a low micromolar inhibitor 17b with good aqueous stability and selectivity over the mammalian serine proteases.