2051-28-7

Basic information

• Product Name: Decahydroquinoline
• Synonyms: DECAHYDROQUINOLINE;2-Azabicyclo[4.4.0]decane;decahydro-quinolin;QUINOLIDINE;DECAHYDROQUINOLINE, 97%, MIXTURE OF CIS AND TRANS;Decahydroquinoline, mixture of cis and trans, 98%;DECAHYDROQUINOLINE(CIS+TRANS);DECAHYDROQUINOLINE (CIS-AND TRANS- MIXTURE)
• CAS NO: 2051-28-7
• Molecular Formula: C₉H₁₇N
• Molecular Weight: 139.24
• EINECS: 218-116-7
• Product Categories: Quinoline&Isoquinoline;Building Blocks;Heterocyclic Building Blocks;Quinolines
• Mol File: 2051-28-7.mol
• Article Data: 39

Chemical Properties

• Melting Point: 37.5-45 °C
• Boiling Point: 245.24°C (rough estimate)
• Flash Point: 155 °F
• Appearance: Clear colorless to light yellow/Melting Solid
• Density: 0.933 g/mL at 25 °C(lit.)
• Vapor Pressure: 0.315mmHg at 25°C
• Refractive Index: n20/D 1.4916(lit.)
• PKA: 10.85±0.10(Predicted)
• CAS DataBase Reference: Decahydroquinoline(CAS DataBase Reference)
• NIST Chemistry Reference: Decahydroquinoline(2051-28-7)
• EPA Substance Registry System: Decahydroquinoline(2051-28-7)

Safety Data

• Hazard Codes: Xi,N,Xn
• Statements: 36/37/38-51/53-22
• Safety Statements: 26-36/37/39-24/25-61
• RIDADR: UN 3082 9/PG 3
• WGK Germany: 3
• Hazardous Substances Data: 2051-28-7(Hazardous Substances Data)

Usage

Description

Decahydroquinoline is a decahydroquinoline derivative characterized by its clear colorless to light yellow appearance and low melting solid properties. It is known for its analgesic activity, making it a potential candidate for pharmaceutical applications.

Uses

Used in Pharmaceutical Industry:
Decahydroquinoline is used as an analgesic agent for its pain-relieving properties. It can be utilized in the development of medications aimed at alleviating pain and discomfort in various conditions.
Used in Chemical Research:
Decahydroquinoline's hydrodenitrogenation has been investigated over Ni-MoS2/γ-Al2O3 and NiMo(P)/Al2O3 catalysts, indicating its potential use in chemical research and development for understanding and optimizing catalytic processes.
Used in Catalyst Development:
The study of decahydroquinoline's hydrodenitrogenation over different catalysts suggests its potential application in the development of new catalysts for various industrial processes, particularly in the field of hydrotreating and hydrocracking.

InChI:InChI=1/C9H17N/c1-2-6-9-8(4-1)5-3-7-10-9/h8-10H,1-7H2/p+1/t8-,9-/m0/s1

Upstream product

• 91-22-5 quinoline 
• 5825-44-5 N-nitroso-1,2,3,4-tetrahydroquinoline 
• 7664-93-9 sulfuric acid 
• 7647-01-0 hydrogenchloride 
• 7732-18-5 water 
• 4629-75-8 (+/-)-cis-octahydro-quinolin-4-one 
• 64-19-7 acetic acid 
• 635-46-1 1,2,3,4-tetrahydroisoquinoline 
• 10034-85-2 hydrogen iodide 
• 64-17-5 ethanol 
• 59-31-4 2-quinolone 
• 612-62-4 2-Chloroquinoline 
• 65745-75-7 bis-(3,4-dihydro-2H-[1]quinolyl)-diazene 
• 29667-75-2 2-amino-cyclohexanepropylamine 

Downstream Products

• 491-34-9 N-methyl-1,2,3,4-tetrahydroquinoline 
• 64-17-5 ethanol 
• 18826-95-4 1.3-butanediol 
• 29667-75-2 2-amino-cyclohexanepropylamine 
• 943415-49-4 (8aR*)-1-(toluene-4-sulfonyl)decahydroquinoline 
• 1258841-15-4 (octahydro-quinolin-1-yl)-(5-phenyl-isothiazol-4-yl)-methanone 
• 94430-32-7 1-benzyldecahydroquinoline 
• 609367-79-5 [(S)-2,2-Dimethyl-1-(octahydro-quinoline-1-carbonyl)-propyl]-carbamic acid benzyl ester 
• 39086-68-5 1-chloroacetyl-decahydro-quinoline 
• 110-15-6 succinic acid 
• 1678-92-8 propylcyclohexane 
• 2539-75-5 1-propylcyclohexene 
• 103-65-1 phenylpropane 
• 1821-39-2 2-propylaniline 

Relevant articles and documents

Organometallic Synthesis of Bimetallic Cobalt-Rhodium Nanoparticles in Supported Ionic Liquid Phases (CoxRh100?x@SILP) as Catalysts for the Selective Hydrogenation of Multifunctional Aromatic Substrates

The synthesis, characterization, and catalytic properties of bimetallic cobalt-rhodium nanoparticles of defined Co:Rh ratios immobilized in an imidazolium-based supported ionic liquid phase (CoxRh100?x@SILP) are described. Following an organometallic approach, precise control of the Co:Rh ratios is accomplished. Electron microscopy and X-ray absorption spectroscopy confirm the formation of small, well-dispersed, and homogeneously alloyed zero-valent bimetallic nanoparticles in all investigated materials. Benzylideneacetone and various bicyclic heteroaromatics are used as chemical probes to investigate the hydrogenation performances of the CoxRh100?x@SILP materials. The Co:Rh ratio of the nanoparticles is found to have a critical influence on observed activity and selectivity, with clear synergistic effects arising from the combination of the noble metal and its 3d congener. In particular, the ability of CoxRh100?x@SILP catalysts to hydrogenate 6-membered aromatic rings is found to experience a remarkable sharp switch in a narrow composition range between Co25Rh75 (full ring hydrogenation) and Co30Rh70 (no ring hydrogenation).

PRODUCTION METHOD OF CYCLIC COMPOUND

PROBLEM TO BE SOLVED: To provide an industrially simple production method of a cyclic compound. SOLUTION: A production method of a cyclic compound includes a step to obtain a reduced form (B) by reducing an unsaturated bond in a ring structure of an aromatic compound (A) by means of catalytic hydrogenation of the aromatic compound (A) or its salt using palladium carbon as a catalyst under a normal pressure, in which the aromatic compound (A) has one or more ring structures selected from a group consisting of a five membered-ring, a six membered-ring, and a condensed ring of the five membered-ring or the six membered-ring with another six membered-ring, a hetero atom can be included in the ring structure, and the aromatic compound (A) can have one or two side chains bonded to the ring structure and does not have any carbon-carbon triple bond in the side chain. SELECTED DRAWING: None COPYRIGHT: (C)2021,JPOandINPIT

Aromatic compound hydrogenation and hydrodeoxygenation method and application thereof

The invention belongs to the technical field of medicines, and discloses an aromatic compound hydrogenation and hydrodeoxygenation method under mild conditions and application of the method in hydrogenation and hydrodeoxygenation reactions of the aromatic compounds and related mixtures. Specifically, the method comprises the following steps: contacting the aromatic compound or a mixture containing the aromatic compound with a catalyst and hydrogen with proper pressure in a solvent under a proper temperature condition, and reacting the hydrogen, the solvent and the aromatic compound under the action of the catalyst to obtain a corresponding hydrogenation product or/and a hydrodeoxygenation product without an oxygen-containing substituent group. The invention also discloses specific implementation conditions of the method and an aromatic compound structure type applicable to the method. The hydrogenation and hydrodeoxygenation reaction method used in the invention has the advantages of mild reaction conditions, high hydrodeoxygenation efficiency, wide substrate applicability, convenient post-treatment, and good laboratory and industrial application prospects.