2053-21-6

Basic information

• Product Name: sodium gallate
• Synonyms: Sodium 3,4,5-trihydroxybenzoate
• CAS NO: 2053-21-6
• Molecular Formula: C7H6O5.Na
• Molecular Weight: 193.11
• EINECS: 218-148-1
• Mol File: 2053-21-6.mol
• Article Data: 0

Chemical Properties

• Boiling Point: 501.1°C at 760 mmHg
• Flash Point: 271°C
• Appearance: /
• Vapor Pressure: 7.32E-11mmHg at 25°C
• CAS DataBase Reference: sodium gallate(CAS DataBase Reference)
• NIST Chemistry Reference: sodium gallate(2053-21-6)
• EPA Substance Registry System: sodium gallate(2053-21-6)

Safety Data

• Hazardous Substances Data: 2053-21-6(Hazardous Substances Data)

Usage

Description

Sodium gallate is an organic sodium salt that is derived from gallic acid by replacing the proton from the carboxy group with a sodium ion. It is known for its various applications in different industries due to its unique properties.

Uses

Used in Anticancer Applications:
Sodium gallate is used as an anticancer agent for its potential to modulate several oncological signaling pathways, including JAK/STAT, RAS/RAF/mTOR, TGF-β1/TGF-β1R, VEGF/VEGFR, and CXCL12/CXCR4 axes. This modulation exerts inhibitory effects on tumor growth and progression, particularly against solid malignancies such as liver, breast, lung, pancreatic, colorectal, and ovarian cancers. Additionally, sodium gallate demonstrates synergistic anticancer effects when combined with conventional chemotherapeutic drugs, enhancing chemo-sensitivity and efficacy in resistant cases.
Used in Drug Delivery Systems:
To overcome the limitations of sodium gallate, novel drug delivery systems have been developed to enhance its applications and efficacy against cancer cells. Various organic and metallic nanoparticles have been employed as carriers for sodium gallate delivery, aiming to improve its delivery, bioavailability, and therapeutic outcomes.
Used in Pharmaceutical Industry:
Sodium gallate is used as a pharmaceutical candidate for its interactions with biopolymers and macromolecules, making it a promising agent for various applications within the industry.
Used in Cosmetics Industry:
Sodium gallate is used as a preservative and antioxidant in the cosmetics industry, thanks to its ability to prevent the growth of microorganisms and protect products from oxidation.
Used in Food Industry:
Sodium gallate is used as an additive in the food industry for its antioxidant properties, which help to extend the shelf life of products and maintain their quality.
Used in Textile Industry:
Sodium gallate is used in the textile industry as a mordant, which helps to fix dyes to fabrics and improve their colorfastness.
Used in Wood Industry:
Sodium gallate is used in the wood industry as a preservative to protect wood from decay and fungal infections, thus enhancing its durability and longevity.

InChI:InChI=1/C7H6O5.Na/c8-4-1-3(7(11)12)2-5(9)6(4)10;/h1-2,8-10H,(H,11,12);/q;+1/p-1