205319-06-8 Usage
Description
Bis(diphenylphosphinophenyl)ether palladium (II) dichloride, also known as Dichloro[bis(diphenylphosphinophenyl)ether]palladium(II), is a light yellow powder that serves as a crucial catalyst in various chemical reactions. It is a member of the palladium complexes and is characterized by its phosphine ligands, which play a significant role in its catalytic activity.
Uses
Used in Chemical Synthesis:
Bis(diphenylphosphinophenyl)ether palladium (II) dichloride is used as a catalyst for cross-coupling reactions, specifically for the synthesis of high stereoselectivity of conjugated Z,E dienes from 2-brom-1,3-dienes. Its application in this context is due to its ability to facilitate the formation of carbon-carbon bonds, which are essential in the creation of complex organic molecules.
Used in Pharmaceutical Industry:
In the pharmaceutical industry, Bis(diphenylphosphinophenyl)ether palladium (II) dichloride is utilized as a catalyst for the synthesis of complex organic compounds that serve as active pharmaceutical ingredients. Its high stereoselectivity in cross-coupling reactions allows for the production of specific isomers, which is crucial for the development of effective and targeted drugs.
Used in Material Science:
Bis(diphenylphosphinophenyl)ether palladium (II) dichloride is also employed in the field of material science, where it is used as a catalyst for the synthesis of advanced materials with specific properties. These materials can be used in various applications, such as electronics, optics, and energy storage, where the precise control of molecular structure is essential for optimal performance.
Reaction
Stereoretentive palladium-catalyzed Kumada-Corriu couplings of alkenyl halides at room temperature.
Highly selective reactions of unbiased alkenyl halides: Negishi-Plus couplings.
Check Digit Verification of cas no
The CAS Registry Mumber 205319-06-8 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 2,0,5,3,1 and 9 respectively; the second part has 2 digits, 0 and 6 respectively.
Calculate Digit Verification of CAS Registry Number 205319-06:
(8*2)+(7*0)+(6*5)+(5*3)+(4*1)+(3*9)+(2*0)+(1*6)=98
98 % 10 = 8
So 205319-06-8 is a valid CAS Registry Number.
InChI:InChI=1/C36H28OP2.2ClH.Pd/c1-5-17-29(18-6-1)38(30-19-7-2-8-20-30)35-27-15-13-25-33(35)37-34-26-14-16-28-36(34)39(31-21-9-3-10-22-31)32-23-11-4-12-24-32;;;/h1-28H;2*1H;/q;;;+2/p-2
205319-06-8Relevant articles and documents
Palladium complexes of P,P and P,S type bidentate ligands: Implication in Suzuki-Miyaura cross-coupling reaction
Saikia, Kokil,Deb, Biswajit,Borah, Bibek Jyoti,Sarmah, Podma Pollov,Dutta, Dipak Kumar
, p. 4293 - 4297 (2012/01/13)
New palladium complexes of the type [PdCl2(η2- P∩P)] (1a,1b) and [PdCl2(η2-P∩S)] (1c,1d) have been synthesised by the reaction of PdCl2 with P,P and P,S type bidentate ligands in 1:1 mol ratio, where,
The effect of the bite angle of diphosphane ligands on activity and selectivity in palladium-catalyzed cross-coupling
Kranenburg, Mirko,Kamer, Paul C. J.,Van Leeuwen, Piet W. N. M.
, p. 155 - 157 (2007/10/03)
The effect of the natural bite angle (βn) of diphosphane ligands on catalyst selectivity and activity in the palladiumcatalyzed cross-coupling of sec-butyl magnesium chloride with bromobenzene was investigated. The calculated natural bite angles range from 78° for dppe (1,2-bisdiphenylphosphanoethane) to 110° for Xantphos. The natural bite angle of diphosphane ligands has a large effect on catalyst selectivity and activity. Both rate and selectivity of the cross-coupling reaction increase with increasing bite angle and reach a maximum value with DPEphos (βn = 102.7° ). Larger bite angles of the diphosphane ligands result in a decreased selectivity and activity.
