20538-24-3

Basic information

• Product Name: ethyl 1-phenyl-1H-indole-2-carboxylate
• CAS NO: 20538-24-3
• Molecular Formula: C₁₇H₁₅NO₂
• Molecular Weight: 265.3065
• Mol File: 20538-24-3.mol
• Article Data: 7

Chemical Properties

• Boiling Point: 358.4°C at 760 mmHg
• Flash Point: 170.5°C
• Density: 1.13g/cm³
• Vapor Pressure: 2.56E-05mmHg at 25°C
• Refractive Index: 1.591
• CAS DataBase Reference: ethyl 1-phenyl-1H-indole-2-carboxylate(CAS DataBase Reference)
• NIST Chemistry Reference: ethyl 1-phenyl-1H-indole-2-carboxylate(20538-24-3)
• EPA Substance Registry System: ethyl 1-phenyl-1H-indole-2-carboxylate(20538-24-3)

Safety Data

• Hazardous Substances Data: 20538-24-3(Hazardous Substances Data)

Upstream product

• 3770-50-1 2-carbethoxyindole 
• 98-80-6 phenylboronic acid 
• 24512-96-7 ethyl (Z)-2-azido-3-phenylacrylate 
• 100-52-7 benzaldehyde 
• 88284-48-4 2-(trimethylsilyl)phenyl trifluoromethanesulfonate 
• 135055-83-3 Ethyl pyruvate 2-(2-methoxyphenyl)phenylhydrazone 
• 28719-46-2 triphenylbismuth bis(trifluoroacetate) 
• 108-86-1 bromobenzene 

Downstream Products

• 142872-83-1 RX 871024 
• 343238-31-3 (1-phenyl-1H-indol-2-yl)methanol 
• 1426681-58-4 C₁₈H₁₅N₃ 
• 856337-27-4 3,3-dibromo-1-phenyl-indolin-2-one 
• 859068-29-4 3,3-dichloro-1-phenylindolin-2-one 
• 108797-02-0 2-(4,5-Dihydro-1H-imidazol-2-yl)-1-phenyl-2,3-dihydro-1H-indole 
• 108797-70-2 ethyl-2,3-dihydro-1-phenylindole-2-carboxylate 

Relevant articles and documents

Construction of N-C Axial Chirality through Atroposelective C-H Olefination of N-Arylindoles by Palladium/Amino Acid Cooperative Catalysis

Direct construction of N-C axial chirality via Pd-catalyzed atroposelective C-H olefination of N-arylindoles is reported. The crucial role of chiral amino acid as a cocatalyst in the regio- and stereocontrol has been disclosed. In this reaction, a wide range of arylindoles and functional alkenes could be well tolerated. Moreover, the practicality and synthetic value of this process were demonstrated by the divers and simple transformations of the products.

N-(piperidin-4-yl)-1H-indole-2-carboxamide derivatives, preparation method thereof, and pharmaceutical composition for use in preventing or treating Urotensin-Ⅱ receptor activity related diseases containing the same as an active ingredient

The present invention relates to N-(piperidin-4-yl)-1H-indole-2-carboxamide derivatives, a preparation method thereof, and a pharmaceutical composition for preventing or treating urotensin-II receptor activity-related diseases comprising the same as activ

Synthesis of polycyclic indolone and pyrroloindolone heterocycles via the annulation of indole- and pyrrole-2-carboxylate esters with arynes

A mild and general method for the synthesis of a variety of polycyclic indolone and pyrroloindolone heterocycles via the reaction of indole- and pyrrole-2-carboxylate esters with arynes has been developed. Georg Thieme Verlag Stuttgart.