20541-49-5

Basic information

• Product Name: BIS(4-CHLOROPHENYL)DISELENIDE
• Synonyms: 1,2-BIS(4-CHLOROPHENYL)DISELANE;BIS(4-CHLOROBENZENE) DISELENIDE;BIS(4-CHLOROPHENYL)DISELENIDE;bis(p-chlorophenyl) diselenide;Diselenide, bis(4-chlorophenyl);4,4μ-Dichlorodiphenyl diselenide, 4-Chlorophenyl diselenide;4,4'-Diselenobis(chlorobenzene);Bis(4-chlorophenyl) perdiselenide
• CAS NO: 20541-49-5
• Molecular Formula: C₁₂H₈Cl₂Se₂
• Molecular Weight: 381.02
• EINECS: 243-864-6
• Mol File: 20541-49-5.mol
• Article Data: 48

Chemical Properties

• Melting Point: 85-88°C
• Boiling Point: 424.2°C at 760 mmHg
• Flash Point: 210.4°C
• Appearance: /solid
• Vapor Pressure: 5.19E-07mmHg at 25°C
• CAS DataBase Reference: BIS(4-CHLOROPHENYL)DISELENIDE(CAS DataBase Reference)
• NIST Chemistry Reference: BIS(4-CHLOROPHENYL)DISELENIDE(20541-49-5)
• EPA Substance Registry System: BIS(4-CHLOROPHENYL)DISELENIDE(20541-49-5)

Safety Data

• Hazard Codes: T,N
• Statements: 23/25-33-50/53
• Safety Statements: 20/21-28-45-60-61
• RIDADR: 2811
• HazardClass: 6.1(b)
• PackingGroup: III
• Hazardous Substances Data: 20541-49-5(Hazardous Substances Data)

Usage

Chemical Properties

Yellow crystalline powder

InChI:InChI=1/C12H8Cl2Se2/c13-9-1-5-11(6-2-9)15-16-12-7-3-10(14)4-8-12/h1-8H

Upstream product

• 57878-20-3 p-chlorobenzeneselenenyl chloride 
• 60805-87-0 p-chlorobenzeneselenenyl bromide 
• 7664-93-9 sulfuric acid 
• 7314-73-0 1-chloro-4-selenocyanatobenzene 
• 7697-37-2 nitric acid 
• 7647-01-0 hydrogenchloride 
• 20753-53-1 4-chlorobenzeneseleninic acid 
• 88367-34-4 (Z)-(5R)-3-(p-chlorophenylseleno)-2-(2-methoxyethylidene)clavam 
• 7452-29-1 sodium O,O-diethyl phosphoroselenoate 
• 26018-88-2 bis(4-chlorophenyl)iodonium bromide 
• 673-41-6 p-chlorobenzenediazonium tetrafluoroborate 
• 34713-70-7 2-Phenylpropanal 
• 2577-48-2 methyl (2S)-pyrrolidine carboxylate 
• 16645-10-6 p-chloroselenophenol 

Downstream Products

• 221639-23-2 η(6)-1,3-bis(4-chlorophenylseleno)benzene-η(5)-(cyclopentadienyl)iron hexafluorophosphate 
• 221639-26-5 η(6)-1,4-bis(4-chlorophenylseleno)benzene-η(5)-(cyclopentadienyl)iron hexafluorophosphate 
• 81388-76-3 2-<<(p-chlorophenyl)selenenyl>methyl>-1-cyclohexanone 
• 132591-61-8 5-<<(p-chlorophenyl)selenenyl>methyl>spiro<3.5>nonan-1-one 
• 1415256-58-4 (S)-methyl 2-((R)-2-((tert-butoxycarbonyl)amino)-3-((4-chlorophenyl)selanyl)propanamido)-3-phenylpropanoate 
• 73971-46-7 3-benzyloxy-1-propenyl p-chlorophenyl selenoxide 
• 73971-47-8 p-chlorophenyl 1-dodecenyl selenoxide 
• 73971-61-6 1-dodecenyl p-chlorophenyl selenide 
• 73971-45-6 p-chlorophenyl vinyl selenoxide 
• 57878-15-6 4-chlorophenyl vinyl selenide 
• 58235-79-3 bis(4-chlorophenyl)selenide 

Relevant articles and documents

Enhancing the Potential of Miniature-Scale DNA-Compatible Radical Reactions via an Electron Donor-Acceptor Complex and a Reversible Adsorption to Solid Support Strategy

DNA-encoded library (DEL) technology is a powerful tool in the discovery of bioactive probe molecules and drug leads. Mostly, the success in DEL technology stems from the molecular diversity of the chemical libraries. However, the construction of DELs has been restricted by the idiosyncratic needs and the required low concentration (～1 mM or less) of the library intermediate. Here, we report visible-light-promoted on-DNA radical coupling reactions via an electron donor-acceptor (EDA) complex and a reversible adsorption to solid support (RASS) strategy. This protocol provides a unique solution to the challenges of increasing the reactivity of highly diluted DNA substrates and reducing the residues of heavy metals from photocatalysts. A series of on-DNA indole sulfone and selenide derivatives were obtained with good to quantitative conversions. It is anticipated that these mild-condition on-DNA radical reactions will significantly improve the chemical diversity of DELs and find widespread utility to DEL construction.

Highly selective radical isothiocyano-chalcogenization of alkenes with NH4SCN in water

In the presence of catalytic amounts of molecular iodine and stoichiometric potassium persulfate, a green, highly chemoselective, regioselective and cis-selective radical isothiocyano-chalcogenization of alkenes with NH4SCN in water is disclosed. This three component reaction features high selectivities, an environmentally benign process, mild conditions, high yields, excellent functional-group tolerance, and broad substrate scope. The resulting products can be further transformed into other molecules with structural similarities of these compounds to bioactive analogs.

Metal-free synthesis of unsymmetrical selenides from pyridinium salts and diselenides catalysed by visible light

We report the first metal-free selenolations of pyridinium salts with diselenides to prepare unsymmetrical organoselenides catalysed by visible light. This protocol is an efficient and green method for the preparation of unsymmetrical organoselenides because metal-free conditions and readily accessible diselenides are used.