205448-66-4 Usage
Description
Methyl 4-chloro-7-methoxyquinoline-6-carboxylate is a chemical compound with the molecular formula C12H9ClNO4. It is a derivative of quinoline, a heterocyclic organic compound with a nitrogen atom in a six-membered aromatic ring. The presence of a chlorine atom at the 4-position, a methoxy group at the 7-position, and a carboxylate group at the 6-position gives this compound unique chemical and biological properties.
Uses
Used in Pharmaceutical Industry:
Methyl 4-chloro-7-methoxyquinoline-6-carboxylate is used as an antimicrobial agent for treating infections after burns. Its ability to inhibit the growth of bacteria and other microorganisms makes it a valuable component in wound care and burn treatment.
Used in Research and Development:
Methyl 4-chloro-7-methoxyquinoline-6-carboxylate is used as a reagent in the preparation of naphthamides, which are inhibitors of vascular endothelial growth factor (VEGF) receptor tyrosine kinase. These inhibitors play a crucial role in various biological processes, including angiogenesis, cell proliferation, and cell migration. By targeting the VEGF receptor, naphthamides can potentially be used in the development of therapeutic agents for various diseases, such as cancer and age-related macular degeneration.
Check Digit Verification of cas no
The CAS Registry Mumber 205448-66-4 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 2,0,5,4,4 and 8 respectively; the second part has 2 digits, 6 and 6 respectively.
Calculate Digit Verification of CAS Registry Number 205448-66:
(8*2)+(7*0)+(6*5)+(5*4)+(4*4)+(3*8)+(2*6)+(1*6)=124
124 % 10 = 4
So 205448-66-4 is a valid CAS Registry Number.
205448-66-4Relevant articles and documents
MULTI-SUBSTITUTED PYRIDONE DERIVATIVES AND MEDICAL USE THEREOF
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, (2021/07/08)
The present invention relates to multi-substituted pyridone derivatives and therapeutic use thereof. In particular, the present invention relates to a compound of formula (I), a preparation method therefor, a pharmaceutical composition comprising the same, as well as use thereof as a tyrosine kinase inhibitor, in particular, use thereof in treating a disease associated with tyrosine kinase activity. Each substituent in the formula (I) is defined as in the specification.
NOVEL POLYMORPHS OF 4-[3-CHLORO-4-(N'-CYCLOPROPYL UREIDO)PHENOXY]-7-METHOXYQUINOLINE-6-CARBOXAMIDE, ITS SALTS AND PROCESS FOR THE PREPARATION THEREOF
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, (2019/06/23)
The present invention relates to novel polymorphs of 4-[3-chloro-4-(N'- cyclopropyl ureido) phenoxy]-7- methoxyquinoline- 6- carboxamide methanesulfonate represented by following structural formula-1a and process for preparation thereof. Further, the pres
Thiazolidone derivative of lovatinib acid and application of thiazolidone derivative
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Paragraph 0018-0020, (2019/11/21)
The invention discloses 4-[3-chlorine group-4-(cyclopropylaminocarbonyl)aminophenoxy]-7-methoxy-6-quinoline formyl thiazolone and application thereof. The structure conforms the general formula (I) (please see the specification of the formula), the effica
