205672-20-4

Basic information

• Product Name: 4-BENZYLOXY-5-BROMO-2-(N,N-DIMETHYLAMINO)PYRIMIDINE
• Synonyms: 4-BENZYLOXY-5-BROMO-2-(N,N-DIMETHYLAMINO)PYRIMIDINE;4-(Benzyloxy)-5-bromo-N,N-dimethylpyrimidin-2-amine
• CAS NO: 205672-20-4
• Molecular Formula: C13H14BrN3O
• Molecular Weight: 308.17
• Mol File: 205672-20-4.mol
• Article Data: 1

Chemical Properties

• Boiling Point: 421.8±53.0 °C(Predicted)
• Appearance: /
• Density: 1.434±0.06 g/cm3(Predicted)
• Storage Temp.: Room temperature.
• PKA: 4.02±0.10(Predicted)
• CAS DataBase Reference: 4-BENZYLOXY-5-BROMO-2-(N,N-DIMETHYLAMINO)PYRIMIDINE(CAS DataBase Reference)
• NIST Chemistry Reference: 4-BENZYLOXY-5-BROMO-2-(N,N-DIMETHYLAMINO)PYRIMIDINE(205672-20-4)
• EPA Substance Registry System: 4-BENZYLOXY-5-BROMO-2-(N,N-DIMETHYLAMINO)PYRIMIDINE(205672-20-4)

Safety Data

• Hazardous Substances Data: 205672-20-4(Hazardous Substances Data)

Upstream product

• 20194-18-7 sodium phenyl-methanolate 
• 124-40-3 dimethyl amine 
• 205672-19-1 2-chloro-4-benzyloxy-5-bromopyrimidine 

Relevant articles and documents

Studies on the synthesis of the derivatives of 5-(dihydroxyboryl)-cytosines and -isocytosines

Boron derivatives of isocytosine, containing a dihydroxyboryl group in the 5-position, have been prepared for the first time. Reaction of appropriate pyrimidines with n-butyllithium and subsequent boronation at -100°C with triethylborate, followed by catalytic hydrogenation, gave hydrolytically stable N,N-dimethyl-5-(dihydroxyboryl)isocytosine 8a and N-methyl-5-(dihydroxyboryl)isocytosine 8b. Theoretical calculations suggest that the corresponding boron derivatives of cytosine cannot be obtained as thermodynamically stable compounds.