20592-42-1 Usage
Description
Estra-1,3,5(10),16-tetraene-3,17-diol diacetate, also known as Estrone Enol Diacetate, is a steroid compound derived from the modification of estrone. It possesses a unique structure with a diacetate group attached to the 3,17 positions, which contributes to its distinct properties and potential applications.
Uses
Used in Pharmaceutical Industry:
Estra-1,3,5(10),16-tetraene-3,17-diol diacetate is used as a substrate for human paroxonases, enzymes that play a crucial role in the detoxification of various harmful substances in the body. Its ability to modulate the activity of these enzymes can have significant implications in the development of therapeutic agents for various diseases.
Used in Biochemical Research:
Estra-1,3,5(10),16-tetraene-3,17-diol diacetate has the potential to be an inhibitor of NADH-oxidase and succinate oxidase, key enzymes involved in cellular respiration and energy production. Its inhibitory effects on these enzymes can be valuable in studying the mechanisms of cellular metabolism and the development of drugs targeting metabolic disorders.
Check Digit Verification of cas no
The CAS Registry Mumber 20592-42-1 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 2,0,5,9 and 2 respectively; the second part has 2 digits, 4 and 2 respectively.
Calculate Digit Verification of CAS Registry Number 20592-42:
(7*2)+(6*0)+(5*5)+(4*9)+(3*2)+(2*4)+(1*2)=91
91 % 10 = 1
So 20592-42-1 is a valid CAS Registry Number.
InChI:InChI=1/C22H26O4/c1-13(23)25-16-5-7-17-15(12-16)4-6-19-18(17)10-11-22(3)20(19)8-9-21(22)26-14(2)24/h5,7,9,12,18-20H,4,6,8,10-11H2,1-3H3
20592-42-1Relevant articles and documents
Preparation of 14,15-secoestra-1,3,5(10)-trien-15-ynes, inhibitors of estradiol dehydrogenase
Auchus, Richard J.,Palmer, James O.,Carrell, H. L.,Covey, Douglas F.
, p. 77 - 96 (1989)
The conversion of estrone to 14,15-secoestratrien-15-ynes, inactivators of estradiol dehydrogenase from human term placenta, is described.The optically pure precursor 7-acetoxy-octahydro-2-phenanthrenecarboxylic acid methyl ester is prepared from estrone
STEREOSELECTIVE REDUCTION OF ALPHA-HYDROXYKETONE
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Page/Page column 8-9, (2012/03/27)
The present invention provides methods for 1, 2-asymmetric reduction of other compounds wherein 1,2- trans diol is present. In particular the present invention discloses preparation of 17β-Estriol and its derivatives having substantially free of 17α-Estriol impurity using an achiral reductant sodium triacetoxy borohydride.
Synthesis of 16α- and 16β-fluoro-17β-estradiol by fluorination of estrone enols
Patrick,Mortezania
, p. 5153 - 5155 (2007/10/02)
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