205999-88-8

Basic information

• Product Name: methyl 4-(4-chlorophenyl)-6-methyl-2-oxo-1,2,3,4-tetrahydropyrimidine-5-carboxylate
• Synonyms: methyl 4-(4-chlorophenyl)-6-methyl-2-oxo-1,2,3,4-tetrahydropyrimidine-5-carboxylate;methyl 4-(4-chlorophenyl)-6-methyl-2-oxo-3,4-dihydro-1H-pyrimidine-5-carboxylate
• CAS NO: 205999-88-8
• Molecular Formula: C₁₃H₁₃ClN₂O₃
• Molecular Weight: 280.70692
• Mol File: 205999-88-8.mol
• Article Data: 107

Chemical Properties

• Appearance: /
• CAS DataBase Reference: methyl 4-(4-chlorophenyl)-6-methyl-2-oxo-1,2,3,4-tetrahydropyrimidine-5-carboxylate(CAS DataBase Reference)
• NIST Chemistry Reference: methyl 4-(4-chlorophenyl)-6-methyl-2-oxo-1,2,3,4-tetrahydropyrimidine-5-carboxylate(205999-88-8)
• EPA Substance Registry System: methyl 4-(4-chlorophenyl)-6-methyl-2-oxo-1,2,3,4-tetrahydropyrimidine-5-carboxylate(205999-88-8)

Safety Data

• Hazardous Substances Data: 205999-88-8(Hazardous Substances Data)

Upstream product

• 105-45-3 acetoacetic acid methyl ester 
• 57-13-6 urea 
• 873-76-7 para-Chlorobenzyl alcohol 
• 104-87-0 4-methyl-benzaldehyde 
• 5315-86-6 4-chlorobenzaldehyde semicarbazone 
• 3848-36-0 4-chlorobenzaldoxime 
• 674-82-8 4-methyleneoxetan-2-one 
• 67-56-1 methanol 
• 104-88-1 4-chlorobenzaldehyde 
• 13086-93-6 (acetyloxy)(4-chlorophenyl)methyl acetate 
• 41464-88-4 (4-chlorophenyl)chloromethyl isocyanate 
• 14205-39-1 methyl (E)-3-aminocrotonate 
• 21351-39-3 monocarbamide dihydrogen sulfate 

Downstream Products

• 1446133-94-3 6-(4-chlorophenyl)-2-(2,4-dimethoxybenzylamino)-5-(methoxycarbonyl)-4-methyl-3,6-dihydropyrimidin-1-ium chloride 
• 1446133-90-9 C₁₉H₁₇BrClN₃O₂*ClH 
• 1446133-88-5 C₂₀H₁₇ClF₃N₃O₂S*ClH 
• 1446133-84-1 C₁₉H₁₆BrClFN₃O₂*ClH 
• 1446133-82-9 C₁₉H₁₇ClN₄O₅*ClH 
• 1428587-08-9 methyl 2-chloro-4-(4-chlorophenyl)-6-methyl-1,4-dihydropyrimidine-5-carboxylate 
• 1446133-80-7 C₁₉H₁₇BrClN₃O₂*ClH 

Relevant articles and documents

Isolation of polyphenol compounds from olive waste and inhibition of their derivatives for α-glucosidase and α-amylase

Olive waste was used as a sustainable resource because it contained a variety of valuable compounds. The polyphenols active fraction from enrichment by microporous resin and extraction with ethyl acetate were analysed by different chromatographic methods.

Fabrication of porous ultrathin carbon nitride nanosheet catalysts with enhanced photocatalytic activity for N- And O-heterocyclic compound synthesis

A simple and efficient photocatalytic method for the synthesis of dihydropyrimidinones (DHPMs) and their derivatives via porous ultrathin carbon nitride nanosheets (p-CNNs) without solvents was demonstrated. The yields of 3,4-dihydropyrimidin-2(1H)-ones/t

CoFe2O4?SiO2-NH2-CoII NPs: An effective magnetically recoverable catalyst for Biginelli reaction

Biginelli reaction entails acid-catalyzed one-pot synthesis of 3,4-dihydropyrimidin-2(1H)-ones (DHPMs) with simply-accessible initial substances, specifically, aldehyde, urea, and active methylene compound. DHPMs have stimulated a resurgence of attention in the previous two decades because of their broad-ranging pharmacological actions and the existence of varied all-natural products. Currently, green methods to asymmetric Biginelli reaction have been researched for anti-inflammatory DHPMs. In materials chemistry, DHPMs are increasingly decision applications in the creation of materials like polymers, adhesives, fabric dyes, etc. In light of the simplicity by which the Biginelli reaction is conducted, numerous interesting prospects expect its exploitation in variety fields. CoFe2O4?SiO2-NH2-CoII is herein turned out to be an effective catalyst at a three-component Biginelli reaction. The yield of the corresponding DHPMs was rather large (20 cases; average 92 percent). Finally, we herein suggest a procedure that shows lots of advantages and benefits such as the whole lack of solvents, mild reaction conditions, comparatively short reaction times. Also, CoFe2O4?SiO2-NH2-CoII NPs catalyst has been readily recovered from the reaction combination and reused, without the decrease of catalytic action.