20605-19-0Relevant articles and documents
Synthesis, cytotoxicity, and in vivo antitumor activity study of parthenolide semicarbazones and thiosemicarbazones
Du, Guohua,Jia, Xinxin,Li, Yan,Liu, Qi,Wang, Shiyi,Zeng, Binglin,Zhang, Chen
, (2020/05/29)
Parthenolide is an important sesquiterpene lactone with potent anticancer activities. In order to further improve its biological activity, a series of parthenolide semicarbazone or thiosemicarbazone derivatives was synthesized and evaluated for their anti
Synthesis and evaluation of new sulfur-containing L-arginine-derived inhibitors of nitric oxide synthase
Ichimori, Kohji,Stuehr, Dennis J.,Atkinson, Robert N.,King, S. Bruce
, p. 1842 - 1848 (2007/10/03)
A series of compounds (7, 8, 10-17, 23) containing new functional groups derived by the combination of the substrate, intermediate, product, and known inhibitors of nitric oxide synthase (NOS) were prepared and evaluated against NOS. While none of the com