2062-29-5Relevant articles and documents
Eine neue Aminoazirin-Reaktion. Bildung von 3,6-Dihydropyrazin-2(1H)-onen
Hugener, Martin,Heimgartner, Heinz
, p. 172 - 179 (1989)
The reaction of 3-(dimethylamino)-2H-azirines 1 and 2-(trifluoromethyl)-1,3-oxazol-5(2H)-ones 5 in MeCN or THF at 50-80 deg leads to 5-(dimethylamino)-3,6-dihydropyrazin-2(1H)-ones 6 (Scheme 3).Reaction mechanisms for the formation of 6 are discussed: eit
Photochemically induced intramolecular radical cyclization reactions with imines
Lefebvre, Corentin,Michelin, Clément,Martzel, Thomas,Djou'Ou Mvondo, Vaneck,Bulach, Véronique,Abe, Manabu,Hoffmann, Norbert
, p. 1867 - 1875 (2018)
The photochemically induced intramolecular hydrogen abstraction or hydrogen atom transfer in cyclic imines 8a,b followed by a cyclization is investigated. Two types of products are observed, one resulting from the formation of a C-C bond, the other from the formation of a C-N bond. A computational study reveals that hydrogen is exclusively transferred to the imine nitrogen leading to a triplet diradical intermediate. After intersystem crossing, the resulting zwitterionic intermediate undergoes cyclization leading to the final product.
Solid Phase Synthesis of (Benzannelated) Six-Membered Heterocycles via Cyclative Cleavage of Resin-Bound Pseudo-Oxazolones
Gr??le, Simone,Vanderheiden, Sylvia,Hodapp, Patrick,Bulat, Bekir,Nieger, Martin,Jung, Nicole,Br?se, Stefan
supporting information, p. 3598 - 3601 (2016/08/16)
A solid supported procedure for the synthesis of benzoxazinones, dihydropyrazinones, quinoxalinones, and dihydrooxazinones using immobilized oxazolones in combination with difunctional nucleophiles as cleavage agent is presented. The scope of the novel me
