20632-57-9Relevant articles and documents
Identification and Biological Evaluation of Novel Type II B-RafV600E Inhibitors
Wang, Peng-Fei,Wang, Ze-Feng,Qiu, Han-Yue,Huang, Yue,Hu, Hui-Min,Wang, Zhong-Chang,Zhu, Hai-Liang
, p. 2558 - 2566 (2018/11/23)
The mitogen-activated protein kinase (MAPK) pathway plays a vital role in signal transduction networks. Severe diseases may be triggered if it is disturbed by mutated components, especially the kinase B-RafV600E. New inhibitors of the kinase ar
Design and synthesis of diphenyl urea derivative anti-tumor compounds containing pyrazol frameworks
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Paragraph 0029, (2017/09/18)
The invention discloses diphenyl urea derivatives containing pyrazol frameworks and a prepration method thereof. The structural formula of the diphenyl urea derivatives containing pyrazol frameworks is as shown in the specification, wherein R1 is selected
Towards the Discrimination of Carboxylates by Hydrogen-Bond Donor Anion Receptors
Kadam, Sandip A.,Martin, Kerli,Haav, Kristjan,Toom, Lauri,Mayeux, Charly,Pung, Astrid,Gale, Philip A.,Hiscock, Jennifer R.,Brooks, Simon J.,Kirby, Isabelle L.,Busschaert, Nathalie,Leito, Ivo
, p. 5145 - 5160 (2015/03/30)
The binding constants (log Kass) of small synthetic receptor molecules based on indolocarbazole, carbazole, indole, urea and some others, as well as their combinations were measured for small carboxylate anions of different basicity, hydrophili