20647-85-2Relevant articles and documents
Synthesis of tetrazolopiperazine building blocks by a novel multi-component reaction
Umkehrer, Michael,Kolb, Jürgen,Burdack, Christoph,Ross, Günther,Hiller, Wolfgang
, p. 6421 - 6424 (2004)
A novel Ugi-five-centre-four-component reaction (U-5C-4CR) of aldehydes, primary amines, trimethylsilylazide and 2-isocyanoethyltosylate yielding tetrazolopiperazine building blocks is described.
One-Pot Synthesis of Cyclic Isothioureas
Wang, Jun,Sun, Zhihua
supporting information, p. 1751 - 1756 (2021/08/27)
The one-pot synthesis of cyclic isothioureas is reported. This method provides a straightforward and efficient approach to the synthesis of a broad range of cyclic isothioureas with yields of up to 90% and in quantities of up to 5 g. It is of great value for the preparation of classic organocatalysts, such as benzotetramisole and homobenzotetramisole.
