206861-69-0

Basic information

• Product Name: {[2-(9-Phenyl-9H-xanthen-9-yloxy)-ethylamino]-methyl}-phosphonic acid dimethyl ester
• Synonyms: {[2-(9-Phenyl-9H-xanthen-9-yloxy)-ethylamino]-methyl}-phosphonic acid dimethyl ester
• CAS NO: 206861-69-0
• Molecular Weight: 439.448
• Mol File: 206861-69-0.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: {[2-(9-Phenyl-9H-xanthen-9-yloxy)-ethylamino]-methyl}-phosphonic acid dimethyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: {[2-(9-Phenyl-9H-xanthen-9-yloxy)-ethylamino]-methyl}-phosphonic acid dimethyl ester(206861-69-0)
• EPA Substance Registry System: {[2-(9-Phenyl-9H-xanthen-9-yloxy)-ethylamino]-methyl}-phosphonic acid dimethyl ester(206861-69-0)

Safety Data

• Hazardous Substances Data: 206861-69-0(Hazardous Substances Data)

Upstream product

• 42506-03-6 pixyl chloride 
• 96851-20-6 trifluoromethanesulfonic acid-[dimethoxyphosphinyl]-methyl ester 
• 206861-68-9 2-(9-Phenyl-9H-xanthen-9-yloxy)-ethylamine 
• 50918-71-3 dimethyl (aminomethyl)phosphonate 

Downstream Products

• 206861-73-6 ({[2-(5-Methyl-2,4-dioxo-3,4-dihydro-2H-pyrimidin-1-yl)-acetyl]-[2-(9-phenyl-9H-xanthen-9-yloxy)-ethyl]-amino}-methyl)-phosphonic acid dimethyl ester 
• 206861-70-3 ({[2-(6-Benzoylamino-purin-9-yl)-acetyl]-[2-(9-phenyl-9H-xanthen-9-yloxy)-ethyl]-amino}-methyl)-phosphonic acid dimethyl ester 
• 206861-71-4 ({[2-(4-Benzoylamino-2-oxo-2H-pyrimidin-1-yl)-acetyl]-[2-(9-phenyl-9H-xanthen-9-yloxy)-ethyl]-amino}-methyl)-phosphonic acid dimethyl ester 

Relevant articles and documents

Synthesis and hybridization properties of an acyclic achiral phosphonate DNA analogue

Protected N-(2-hydroxyethyl)-N-(nucleobase- acetyl)aminomethanephosphonic acids (6a-d) of all four DNA nucleobases have been prepared and oligomerized by solid-phase synthesis. Four DNA decamers containing 1-10 of these 'PPNA' monomers were prepared and evaluated by T(m) measurements (medium salt) for binding to their DNA and RNA complements. One central modification reduced the binding strongly (?T(m) =-10 °C), but contiguous PPNA monomers gave smaller effects, and the all-PPNA decamer bound to RNA with a ?T(m) of -1.2°C per modification. Thus PPNA oligomers are inferior DNA and RNA binders compared to the closely related and strongly binding PNA oligomers.