207128-19-6Relevant articles and documents
Newly synthesized L-enantiomers of 3'-fluoro-modified β-2'- deoxyribonucleoside 5'-triphosphates inhibit hepatitis B DNA polymerases but not the five cellular DNA polymerases α, β, Γ, δ, and ε nor HIV-1 reverse transcriptase
Von Janta-Lipinski, Martin,Costisella, Burkhardt,Ochs, Hansueli,Hübscher, Ulrich,Hafkemeyer, Peter,Matthes, Eckart
, p. 2040 - 2046 (2007/10/03)
Novel β-L-2',3'-dideoxy-3'-fluoro nucleosides were synthesized and further converted to their 5'-triphosphates. Their inhibitory activities against hepatitis B virus (HBV) and duck hepatitis B virus (DHBV) DNA polymerases, α, ?, γ, δ and ε were investigat