207386-91-2 Usage
Description
8-Hydroxyquinoline sulfate monohydrate, also known as 8-Hydroxyquinoline Hemisulfate Salt Hemihydrate, is a yellow crystalline powder or lumps with significant pharmacological and biological properties. It functions as a 20S proteasome inhibitor, playing a crucial role in various applications across different industries.
Uses
Used in Pharmaceutical Industry:
8-Hydroxyquinoline sulfate monohydrate is used as a pharmacological agent for the study and treatment of drug-resistant bacterial and fungal infections. Its metal chelating properties, particularly with clioquinol analogs, make it a valuable compound in combating resistant infections.
Used in Combination Therapy:
In the field of antibiotic research, 8-Hydroxyquinoline sulfate monohydrate is used as an adjunct to enhance the efficacy of other antibiotics. It is particularly useful in combination with β-lactamase inhibitors, which help to improve the effectiveness of β-lactam antibiotics against resistant bacteria.
Used in Biological Studies:
8-Hydroxyquinoline sulfate monohydrate is also utilized in biological research as a tool to investigate the role of the 20S proteasome in various cellular processes. Its inhibitory action on the proteasome can provide insights into the mechanisms of protein degradation and its implications in disease progression and treatment.
Biochem/physiol Actions
It is a potential copper ligand and is a tested effective proteasome inhibitor.
Check Digit Verification of cas no
The CAS Registry Mumber 207386-91-2 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 2,0,7,3,8 and 6 respectively; the second part has 2 digits, 9 and 1 respectively.
Calculate Digit Verification of CAS Registry Number 207386-91:
(8*2)+(7*0)+(6*7)+(5*3)+(4*8)+(3*6)+(2*9)+(1*1)=142
142 % 10 = 2
So 207386-91-2 is a valid CAS Registry Number.
InChI:InChI=1/2C9H7NO.H2O4S.H2O/c2*11-8-5-1-3-7-4-2-6-10-9(7)8;1-5(2,3)4;/h2*1-6,11H;(H2,1,2,3,4);1H2
