207446-89-7 Usage
General Description
Arteannuin L is a sesquiterpene lactone compound that is isolated from the traditional Chinese medicinal herb Artemisia annua. It has been found to possess significant anti-malarial activity, particularly against Plasmodium falciparum, the parasite responsible for the most lethal form of malaria. Arteannuin L has been shown to inhibit the growth of the parasite at multiple stages of its life cycle, making it a promising candidate for the development of new anti-malarial drugs. Additionally, it has also exhibited anti-inflammatory and anticancer properties, further highlighting its potential for therapeutic applications beyond malaria treatment.
Check Digit Verification of cas no
The CAS Registry Mumber 207446-89-7 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 2,0,7,4,4 and 6 respectively; the second part has 2 digits, 8 and 9 respectively.
Calculate Digit Verification of CAS Registry Number 207446-89:
(8*2)+(7*0)+(6*7)+(5*4)+(4*4)+(3*6)+(2*8)+(1*9)=137
137 % 10 = 7
So 207446-89-7 is a valid CAS Registry Number.
207446-89-7Relevant articles and documents
Structure elucidation of arteannuin O, a novel cadinane diol from Artemisia annua, and the synthesis of arteannuins K, L, M and O
Sy, Lai-King,Cheung, Kung-Kai,Zhu, Nian-Yong,Brown, Geoffrey D
, p. 8481 - 8493 (2007/10/03)
The novel cadinane diol, arteannuin O (1), has been obtained from Artemisia annua and its structure has been established by 2D NMR and X-ray crystallography. A reconstructive synthesis of arteannuin O from artemisinin is described, which also yields the natural products arteannuin K and arteannuin L. Mechanistic considerations have led to the conclusion that the stereochemistry of the 5-hydroxyl group was wrongly assigned when arteannuins K, L and M were first reported as natural products. This was confirmed by derivatization of synthetic arteannuins K, L and M as their Mosher esters.
