207516-21-0

Basic information

• Product Name: Acetic acid (1R,2S,3S,4S,5R)-2,3,4-triacetoxy-1-acetoxymethyl-5-phenylacetylamino-cyclopentyl ester
• CAS NO: 207516-21-0
• Molecular Weight: 507.494
• Mol File: 207516-21-0.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: Acetic acid (1R,2S,3S,4S,5R)-2,3,4-triacetoxy-1-acetoxymethyl-5-phenylacetylamino-cyclopentyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: Acetic acid (1R,2S,3S,4S,5R)-2,3,4-triacetoxy-1-acetoxymethyl-5-phenylacetylamino-cyclopentyl ester(207516-21-0)
• EPA Substance Registry System: Acetic acid (1R,2S,3S,4S,5R)-2,3,4-triacetoxy-1-acetoxymethyl-5-phenylacetylamino-cyclopentyl ester(207516-21-0)

Safety Data

• Hazardous Substances Data: 207516-21-0(Hazardous Substances Data)

Upstream product

• 108-24-7 acetic anhydride 
• 39939-07-6 5-(benzyloxymethyl)cyclopentadiene 
• 207516-12-9 Acetic acid (1S,2R,3R,4R,5S)-2,3-diacetoxy-5-((S)-2-acetoxy-2-phenyl-acetylamino)-4-benzyloxymethyl-cyclopentyl ester 
• 207516-15-2 Acetic acid (1S,2R,3R,4R,5S)-2,3-diacetoxy-4-hydroxymethyl-5-phenylacetylamino-cyclopentyl ester 
• 207516-17-4 Acetic acid (1S,2R,3R,5S)-2,3-diacetoxy-4-methylene-5-phenylacetylamino-cyclopentyl ester 
• 207516-06-1 (S)-N-((1R,4S,5R)-5-Benzyloxymethyl-4-hydroxy-cyclopent-2-enyl)-2-hydroxy-2-phenyl-acetamide 
• 207516-08-3 Acetic acid (1S,4R,5R)-4-((S)-2-acetoxy-2-phenyl-acetylamino)-5-benzyloxymethyl-cyclopent-2-enyl ester 
• 124097-40-1 (2S)-(+)-2-hydroxy-2-phenylacetohydroxamic acid 

Downstream Products

• 160868-00-8 (3aR,4R,5S,6R,6aS)-4-Hydroxymethyl-2-((2S,3R,4S,5R,6R)-3,4,5-tris-benzyloxy-6-benzyloxymethyl-tetrahydro-pyran-2-ylamino)-4,5,6,6a-tetrahydro-3aH-cyclopentaoxazole-4,5,6-triol 
• 160401-04-7 1-((1R,2R,3S,4S,5S)-2,3,4,5-Tetrahydroxy-2-hydroxymethyl-cyclopentyl)-3-((2S,3R,4S,5R,6R)-3,4,5-tris-benzyloxy-6-benzyloxymethyl-tetrahydro-pyran-2-yl)-thiourea 

Relevant articles and documents

Enantioselective approaches to aminocyclopentitols: A total synthesis of (+)-6-epitrehazolin and a formal total synthesis of (+)-trehazolin

Potent inhibitors of trehalase, such as trehazolin and its congeners, represent an attractive approach to the design of effective new insect control agents. In this report, enantioselective total syntheses of (-)-6- epitrehazolin and (+)-trehazolin were achieved using the asymmetric heterocycloaddition between [(benzyloxy)methyl]cyclopentadiene and the acylnitroso compound arising from in situ oxidation of (S)-mandelohydroxamic acid with tetrabutylammonium periodate. Further functionalization of the resulting 3,4,5-trisubstituted cyclopentene, either involving osmylation or epoxidation of the double bond, efficiently created pentasubstituted cyclopentanes. Introduction of the quaternary carbon in both synthesis targets was achieved via stereoselective osmylation of an intermediate 2,3,4,5-substituted 1-methylenecyclopentane.