207680-02-2

Basic information

• Product Name: 10-isobutyloyl 10-deacetylbaccatin III
• Synonyms: 10-isobutyloyl 10-deacetylbaccatin III
• CAS NO: 207680-02-2
• Molecular Weight: 614.69
• Mol File: 207680-02-2.mol
• Article Data: 3

Chemical Properties

• CAS DataBase Reference: 10-isobutyloyl 10-deacetylbaccatin III(CAS DataBase Reference)
• NIST Chemistry Reference: 10-isobutyloyl 10-deacetylbaccatin III(207680-02-2)
• EPA Substance Registry System: 10-isobutyloyl 10-deacetylbaccatin III(207680-02-2)

Safety Data

• Hazardous Substances Data: 207680-02-2(Hazardous Substances Data)

Upstream product

• 32981-86-5 10-deacetylbaccatin III 
• 97-72-3 2-Methylpropionic anhydride 
• 79-30-1 isobutyryl chloride 

Downstream Products

• 709632-99-5 C₃₉H₅₆O₁₁Si 
• 709633-04-5 C₄₅H₇₀O₁₁Si₂ 
• 709633-32-9 C₅₅H₆₈N₄O₁₄Si 
• 709633-33-0 C₅₅H₆₈ClNO₁₄Si 
• 709633-54-5 C₅₄H₇₅NO₁₄Si 
• 709633-44-3 C₅₃H₇₃NO₁₅Si 
• 709633-50-1 C₅₃H₆₇NO₁₅Si 
• 709633-21-6 C₄₅H₆₉N₃O₁₁Si₂ 
• 709633-17-0 C₄₅H₆₉ClO₁₁Si₂ 
• 566899-42-1 2-debenzoyl-2-m-azidobenzoyl-10-deacetyl-10-isobutanoyl-7-triethylsilylbaccatin III 
• 566899-43-2 2-debenzoyl-2-m-chlorobenzoyl-10-deacetyl-10-isobutanoyl-7-triethylsilylbaccatin III 
• 566899-34-1 2-debenzoyl-2-m-azidobenzoyl-10-deacetyl-10-isobutanoylbaccatin III 
• 566899-35-2 2-debenzoyl-2-m-chlorobenzoyl-10-deacetyl-10-isobutanoylbaccatin III 

Relevant articles and documents

Lanthanide trifluoromethanesulfonate catalysed selective acylation of 10-deacetylbaccatin III

The selective C-10 acylation of 10-deacetylbaccatin III to baccatin III and derivatives is very efficiently catalysed by lanthanide trifluoromethanesulfonates. Baccatin III, now readily available through this procedure, is an important precursor for an economically viable semisynthesis of paclitaxel and its derivatives.

Synthesis and biological evaluation of C-3′NH/C-10 and C-2/C-10 modified paclitaxel analogues

Concurrent modifications on the C-3′NH/C-10, and C-2/C-10 positions on paclitaxel were carried out as a way of investigating possible synergistic effects. The biological activities of these analogues were evaluated in both a microtubule assembly assay and