20772-70-7

Basic information

• Product Name: Phenol, 4-methoxy-2-[(phenylimino)methyl]-
• CAS NO: 20772-70-7
• Molecular Formula: C14H13NO2
• Molecular Weight: 227.263
• Mol File: 20772-70-7.mol
• Article Data: 6

Chemical Properties

• CAS DataBase Reference: Phenol, 4-methoxy-2-[(phenylimino)methyl]-(CAS DataBase Reference)
• NIST Chemistry Reference: Phenol, 4-methoxy-2-[(phenylimino)methyl]-(20772-70-7)
• EPA Substance Registry System: Phenol, 4-methoxy-2-[(phenylimino)methyl]-(20772-70-7)

Safety Data

• Hazardous Substances Data: 20772-70-7(Hazardous Substances Data)

Upstream product

• 672-13-9 2-hydroxy-5-methoxybenzaldehyde 
• 62-53-3 aniline 

Downstream Products

• 1360873-59-1 (3aS,4R,9aR)-6-methoxy-N-phenyl-3,3a,4,9a-tetrahydro-2H-furo[2,3-b]chromen-4-amine 
• 1322617-95-7 N-(3-benzyl-6-methoxy-2-oxo-4-(phenylamino)chroman-3-yl)benzamide 
• 1322617-93-5 N-(3-benzyl-6-methoxy-2-oxo-4-(phenylamino)chroman-3-yl)benzamide 
• 1227260-77-6 7-methoxy-N-phenyl-2,3,4,4a,5,10a-hexahydropyrano[2,3-b]chromene-4-amine 
• 1227260-64-1 6-methoxy-N-phenyl-3,3a,4,9a-tetrahydro-2H-furo[2,3-b]chromene-4-amine 
• 84821-31-8 Cu(CH₃OC₆H₃(O)CHNC₆H₅)2 
• 84819-29-4 N-phenyl-2-(aminomethyl)-4-methoxyphenol 
• 132120-41-3 6-Methoxy-3-phenyl-3,4-dihydro-2H-benzo[e][1,3]oxazine 

Relevant articles and documents

Copper-Catalyzed Asymmetric Annulation Reactions of Carbenes with 2-Iminyl- or 2-Acyl-Substituted Phenols: Convenient Access to Enantioenriched 2,3-Dihydrobenzofurans

We have developed a method for the highly diastereo- and enantioselective construction of 2,3-dihydrobenzofurans bearing tetrasubstituted carbon stereocenters by means of annulation reactions between carbenes and 2-iminyl- or 2-acyl-substituted phenols through catalysis by readily accessible copper(I)/bisoxazoline catalysts under mild conditions. These reactions feature a unique mechanism in which the copper catalyst serves a dual function: first it reacts with the diazo compound to generate a metal carbene, and second, upon formation of an oxonium ylide, it acts as a Lewis acid to activate the imine or ketone for diastereo- and enantioselective cyclization.

Sulfonic acid supported on hydroxyapatite-encapsulated-γ-Fe 2O3 nanocrystallites as a magnetically separable catalyst for one-pot reductive amination of carbonyl compounds

A novel, environmentally friendly procedure has been developed for the preparation of secondary or tertiary amines by one-pot reductive amination of carbonyl compounds using sodium borohydride in the presence of a magnetically recoverable sulfonic acid supported on hydroxyapatite-encapsulated-γ- Fe2O3 [γ-Fe2O3@HAP-SO 3H] at room temperature. The catalyst was easily separated from the reaction mixture by applying an external magnet and reused for six cycles without significant loss of catalytic activity.

Qualitative analysis of the stability of the oxazine ring of various benzoxazine and pyridooxazine derivatives with proton nuclear magnetic resonance spectroscopy

A series of 3,4-dihydro-1,3-benzoxazine and 3,4-dihydro-1,3-pyridooxazine derivatives was synthesized, and the hydrolysis of the derivatives was studied with proton nuclear magnetic resonance spectroscopy. The oxazine derivatives underwent various degrees of hydrolysis when H2O was added to dimethyl sulfoxide solutions of the compounds. The rates and extents of decomposition of the oxazine ring systems depended on the electronic effects of substituents within the molecules. Examination of the proton nuclear magnetic resonance spectra that were generated during decomposition of the oxazines and trends in stability of the oxazine derivatives suggest the formation of an intermediate in the hydrolysis mechanism.