207742-80-1

Basic information

• Product Name: TRIBUTYL BORATE-10B, 98 ATOM % 10B
• Synonyms: TRIBUTYL BORATE-10B, 98 ATOM % 10B
• CAS NO: 207742-80-1
• Molecular Formula: C12H27BO3
• Molecular Weight: 230.15198
• Mol File: 207742-80-1.mol
• Article Data: 5

Chemical Properties

• Melting Point: −70 °C(lit.)
• Boiling Point: 230-235 °C(lit.)
• Flash Point: 200 °F
• Appearance: /
• Density: 0.85 g/mL at 25 °C(lit.)
• Refractive Index: n20/D 1.408(lit.)
• CAS DataBase Reference: TRIBUTYL BORATE-10B, 98 ATOM % 10B(CAS DataBase Reference)
• NIST Chemistry Reference: TRIBUTYL BORATE-10B, 98 ATOM % 10B(207742-80-1)
• EPA Substance Registry System: TRIBUTYL BORATE-10B, 98 ATOM % 10B(207742-80-1)

Safety Data

• Hazard Codes: Xn
• Statements: 20/21/22-36/37/38
• Safety Statements: 26-36/37/39
• WGK Germany: 3
• Hazardous Substances Data: 207742-80-1(Hazardous Substances Data)

Upstream product

• 13813-79-1 [10B]boric acid 
• 71-36-3 butan-1-ol 
• 11113-50-1 boric acid 

Relevant articles and documents

Novel Convenient Synthesis of 10B-Enriched Sodium Borohydride

A convenient and efficient synthesis of 10B-enriched sodium borohydride [Na10BH4] from commercially available 10B-enriched boric acid [10B(OH)3] is described. The reaction sequence 10B(OH)3 → 10B(On-Bu)3 → 10BH3·Et3N → Na10BH4 afforded the product in 60-80% yield. The reaction was successfully scaled to hundreds of gram per run.

Preparation method of 4-(borono-10B)-L-phenylalanine

The invention discloses a preparation method of 4-(borono-10B)-L-phenylalanine. The preparation method comprises the following steps: preparing an intermediate, namely N-Boc-4-(borono-10B)-L-phenylalanine by from N-Boc-4-iodo-L-phenylalanine and tri-n-butyl 10-borate; and adding N-Boc-4-(borono-10B)-L-phenylalanine and acetone into a reactor, adding a hydrochloric acid solution, conducting uniformstirring at room temperature, performing heating for a reaction, conducting distilling to remove acetone, reducing the temperature of a residual reaction solution to 10 DEG C or below, regulating a pH value to 5.5-6.5, separating out white solids, filtering out the white solids, conducting pulping and washing with dichloromethane, filtering out the residual solids, and carrying out vacuum dryingto obtain 4-(borono-10B)-L-phenylalanine. By changing a feeding sequence and controlling a reaction rate, the requirement of the reaction on the temperature is lowered, the reaction can be smoothly carried out under a relatively mild low-temperature condition, the consumption of n-butyllithium and borate is reduced, post-reaction treatment is simpler, yield is higher, production cost is greatly saved, and industrialization of the product is made possible.

SYNTHESIS OF BORANE COMPOUNDS

The present invention is directed to a process for the synthesis of alkali metal tetrahydroborates-10B and amine borane-10B precursors, such as sodium tetrahydroborate-10B and triethylamine borane-10B.