207805-98-9

Basic information

• Product Name: 2-(3-Benzoyl-phenyl)-propionic acid 2-formyl-phenyl ester
• Synonyms: 2-(3-Benzoyl-phenyl)-propionic acid 2-formyl-phenyl ester
• CAS NO: 207805-98-9
• Molecular Weight: 358.394
• Mol File: 207805-98-9.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 2-(3-Benzoyl-phenyl)-propionic acid 2-formyl-phenyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: 2-(3-Benzoyl-phenyl)-propionic acid 2-formyl-phenyl ester(207805-98-9)
• EPA Substance Registry System: 2-(3-Benzoyl-phenyl)-propionic acid 2-formyl-phenyl ester(207805-98-9)

Safety Data

• Hazardous Substances Data: 207805-98-9(Hazardous Substances Data)

Upstream product

• 59512-44-6 ketoprofen chloride 
• 90-02-8 salicylaldehyde 
• 22071-15-4 ketoprofen 

Downstream Products

• 22071-15-4 ketoprofen 
• 90-02-8 salicylaldehyde 

Relevant articles and documents

Prodrugs: Part 3. 2-Formylphenyl esters of indomethacin, ketoprofen and ibuprofen and 6-substituted 2-formyl and 2-acylphenyl esters of aspirin

The synthesis and study of a novel series of potential prodrugs of indomethacin, ketoprofen, ibuprofen and aspirin are reported. 2-Formylphenyl esters of the NSAIDs, together with two 6-substituted 2-formyl and two 2-acylphenyl aspirins and 4-formylphenyl indomethacin, have been prepared. A study of their alkaline and neutral hydrolysis shows that these compounds, with the exception of 2-acetylphenyl aspirin, act as true prodrugs of the NSAIDs, giving the NSAID and acylphenol. The rates of hydrolysis and activation parameters indicate that the 2-acylphenyl esters employ an intramolecular catalytic route. The 2-formylphenyl esters were more potent as anti-inflammatory agents than the parent compounds in the carragheenan-induced paw oedema test.