207845-32-7

Basic information

• Product Name: 3-(2-PHENYLETHYNYL)BENZOIC ACID ETHYL ESTER
• Synonyms: methyl 3-(phenylethynyl)benzoate;3-(2-PHENYLETHYNYL)BENZOIC ACID ETHYL ESTER
• CAS NO: 207845-32-7
• Molecular Formula: C₁₆H₁₂O₂
• Molecular Weight: 236.27
• Mol File: 207845-32-7.mol
• Article Data: 12

Chemical Properties

• Appearance: /
• CAS DataBase Reference: 3-(2-PHENYLETHYNYL)BENZOIC ACID ETHYL ESTER(CAS DataBase Reference)
• NIST Chemistry Reference: 3-(2-PHENYLETHYNYL)BENZOIC ACID ETHYL ESTER(207845-32-7)
• EPA Substance Registry System: 3-(2-PHENYLETHYNYL)BENZOIC ACID ETHYL ESTER(207845-32-7)

Safety Data

• Hazardous Substances Data: 207845-32-7(Hazardous Substances Data)

Upstream product

• 618-91-7 methyl 3-iodo-benzoate 
• 536-74-3 phenylacetylene 
• 2905-65-9 methyl 3-chlorobenzoate 
• 108-90-7 chlorobenzene 
• 115-19-5 2-methyl-but-3-yn-2-ol 
• 618-89-3 methyl 3-bromobenzoate 
• 2170-06-1 1-Phenyl-2-(trimethylsilyl)acetylene 
• 67-56-1 methanol 
• 3757-88-8 tributylstannylethynylbenzene 
• 618-51-9 3-Iodobenzoic acid 

Downstream Products

• 194605-54-4 3-phenethylbenzoic acid methyl ester 
• 93866-50-3 3-(2-phenylethynyl)benzoic acid 
• 74070-40-9 [3-((Z)-Styryl)-phenyl]-methanol 
• 123926-88-5 [3-(2-phenylethynyl)phenyl]methanol 

Relevant articles and documents

Palladium-catalyzed efficient and one-pot synthesis of diarylacetylenes from the reaction of aryl chlorides with 2-methyl-3-butyn-2-ol

An efficient and practical synthetic method has been developed for the preparation of symmetrical diarylacetylenes from the direct reaction of aryl chlorides with 2-methyl-3-butyn-2-ol catalyzed by palladium(II) chloride-bis(tricyclohexylphosphine) [PdCl2(PCy3) 2] under mild reaction conditions. Unsymmetrical diarylated acetylenes could be also obtained by using two different aryl chlorides simultaneously. The catalytic procedure includes a novel one-pot palladium-catalyzed, double Sonogashira coupling of inactivated aryl chlorides without use of copper(1) as co-catalyst.

Recyclable Pd/CuFe2O4 nanowires: A highly active catalyst for C-C couplings and synthesis of benzofuran derivatives

Pd/CuFe2O4 nanowire-catalyzed cross coupling transformations are described. Notably, these reactions showed excellent functional group tolerance. Further, the protocol is applied to a one-pot synthesis of benzofurans via a Sonogashira coupling and intramolecular etherification sequence. The catalyst was reused and found to maintain its activity and stability.

HYDROXAMIC ACID DERIVATIVES AS GRAM-NEGATIVE ANTIBACTERIAL AGENTS

The invention relates to chemical compounds of formula (IB): or a salt thereof. In some embodiments, the invention relates to inhibitors of UDP-3-0 — (R-S-hydroxymyristoyl)-N-acetylglucosamine deacetylase (LpxC). In still further embodiments, the invention relates to pharmaceutical compositions comprising compounds disclosed herein and their use in the prevention and/or treatment of Gram- negative bacterial infections.