2079-95-0 Usage
Description
1-Tetradecanethiol (TDT) is an alkanethiol that forms self-assembled monolayers (SAMs) on various surfaces, particularly gold nanoparticles. It is a hydrophobic ligand with a highly oriented structure, serving as a hole-injection barrier on nanoparticle surfaces. TDT is a colorless liquid and is widely used for functionalizing nanoparticles in different applications.
Uses
Used in Biomedical Applications:
1-Tetradecanethiol is used as a self-assembled monolayer (SAM) on gold nanoparticle (AuNP) based electrodes for bi-enzyme glucose biosensors. The surface modification is achieved by soaking the electrodes in TDT solution, which enhances the performance and sensitivity of the biosensors.
Used in Nanotechnology:
1-Tetradecanethiol is used as a functionalizing agent for various nanoparticles, including gold nanoparticles. Its hydrophobic nature and highly oriented structure make it an ideal candidate for modifying the surface properties of nanoparticles, improving their stability, biocompatibility, and performance in various applications.
Used in Electronics:
1-Tetradecanethiol acts as a hole-injection barrier on the surface of nanoparticles, making it useful in the development of electronic devices and components. Its ability to modify the surface properties of nanoparticles can lead to improved performance and efficiency in electronic applications.
Check Digit Verification of cas no
The CAS Registry Mumber 2079-95-0 includes 7 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 4 digits, 2,0,7 and 9 respectively; the second part has 2 digits, 9 and 5 respectively.
Calculate Digit Verification of CAS Registry Number 2079-95:
(6*2)+(5*0)+(4*7)+(3*9)+(2*9)+(1*5)=90
90 % 10 = 0
So 2079-95-0 is a valid CAS Registry Number.
InChI:InChI=1/C14H30S/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-15/h15H,2-14H2,1H3
2079-95-0Relevant articles and documents
Synthesis of a tetronic acid library focused on inhibitors of tyrosine and dual-specificity protein phosphatases and its evaluation regarding VHR and Cdc25B inhibition
Sodeoka,Sampe,Kojima,Baba,Usui,Ueda,Osada
, p. 3216 - 3222 (2007/10/03)
Selective inhibitors of protein tyrosine phosphatases (PTPs) and dual-specificity phosphatases (DSPs) are expected to be useful tools for clarifying the biological functions of the PTPs themselves and also to be candidates for novel therapeutics. We planned a library approach for the identification of PTP/DSP inhibitors in which 3-acyltetronic acid is used as a "core" phosphate mimic. A series of novel tetronic acid derivatives were synthesized and evaluated as inhibitors of the dual-specificity protein phosphatases VHR and cdc25B. Several compounds are found to be potent inhibitors of cdc25B, which is a key enzyme for cell-cycle progression. The promising results described herein strongly indicated that this tetronic acid library is potent as a library focused on the PTP/DSP-selective inhibitor.
