20816-79-9 Usage
Description
1-Bromo-8-chloronaphthalene is an organic compound that belongs to the class of halogenated aromatic hydrocarbons. It is characterized by the presence of a bromine atom at the 1-position and a chlorine atom at the 8-position on the naphthalene ring. 1-Bromo-8-chloronaphthalene exhibits unique chemical properties due to the presence of these halogen atoms, making it a valuable intermediate in various chemical reactions.
Uses
Used in Organic Synthesis:
1-Bromo-8-chloronaphthalene is used as a reagent in the preparation of peri-substituted naphthalene series. The presence of bromine and chlorine atoms at the 1 and 8 positions, respectively, allows for selective functionalization and substitution reactions, enabling the synthesis of a wide range of naphthalene-based compounds with diverse applications in various industries.
Used in Pharmaceutical Industry:
1-Bromo-8-chloronaphthalene can be used as a building block for the synthesis of pharmaceutical compounds. The halogenated naphthalene core can be further modified to incorporate various functional groups, leading to the development of new drugs with potential therapeutic applications.
Used in Chemical Research:
1-Bromo-8-chloronaphthalene serves as a valuable research tool in the field of organic chemistry. Its unique structure and reactivity make it an ideal candidate for studying various chemical reactions and mechanisms, contributing to the advancement of chemical knowledge and the development of new synthetic methodologies.
Used in Dye and Pigment Industry:
1-Bromo-8-chloronaphthalene can be employed as a precursor for the synthesis of dyes and pigments. The halogenated naphthalene structure can be further functionalized to produce a variety of colored compounds, which can be used in the production of inks, paints, and other coloring materials.
Check Digit Verification of cas no
The CAS Registry Mumber 20816-79-9 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 2,0,8,1 and 6 respectively; the second part has 2 digits, 7 and 9 respectively.
Calculate Digit Verification of CAS Registry Number 20816-79:
(7*2)+(6*0)+(5*8)+(4*1)+(3*6)+(2*7)+(1*9)=99
99 % 10 = 9
So 20816-79-9 is a valid CAS Registry Number.
20816-79-9Relevant articles and documents
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Bergmann,Hirshberg
, p. 331,334 (1936)
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COVALENT RAS INHIBITORS AND USES THEREOF
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, (2021/06/04)
The disclosure features compounds, or pharmaceutically acceptable salts thereof, alone and in combination with other therapeutic agents, pharmaceutical compositions, and protein conjugates thereof, capable of modulating biological processes including Ras, and their uses in the treatment of cancers.
KRAS G12C INHIBITORS
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, (2020/07/25)
The present invention relates to compounds that inhibit KRas G12C. In particular, the present invention relates to compounds that irreversibly inhibit the activity of KRas G12C, pharmaceutical compositions comprising the compounds and methods of use therefor.
