208347-64-2Relevant articles and documents
A total synthesis of (1R,5R)-3-phenylmethyl-4-thia-2,6-diazabicyclo [3.2.0]hept-2-en-7-one, a useful intermediate for the preparation of penem and cepham derivatives
Cainelli, Gianfranco,Giacomini, Daria,Galletti, Paola
, p. 289 - 294 (2007/10/03)
The preparation of the thiazoline (1R,5R)-3-phenylmethyl-4-thia-2,6- diazabicyclo [3.2.0]hept-2-en-7-one (1) is presented. This compound, which has been extensively used as an intermediate for the synthesis of penems and cephams, has been obtained starting from a C-4 unsubstituted azetidinone by means of facile processes while chirality has been obtained through enzymatic resolution.
Ruthenium Catalyzed Oxidation of 3-Amino-β-Lactams
Cainelli, Gianfranco,DaCol, Marco,Galletti, Paola,Giacomini, Daria
, p. 923 - 924 (2007/10/03)
3-Aminoazetidin-2-ones were converted into the corresponding 4-acetoxy derivatives by treatment with AcOOH and ruthenium on carbon as catalyst.