20897-85-2 Usage
Description
2-Thiophenecarboxylic acid, also known as 2-thiophene carboxylic acid, is a chemical compound with the molecular formula C5H4O2S. It is an ion with a charge of -1. This white to off-white powder is soluble in water and various organic solvents, making it a versatile building block in the synthesis of pharmaceuticals, agrochemicals, and other organic compounds.
Uses
Used in Pharmaceutical Industry:
2-Thiophenecarboxylic acid, ion(1-) is used as a key intermediate in the synthesis of various pharmaceuticals for its unique properties and reactivity. It plays a crucial role in the development of new drugs and the improvement of existing ones.
Used in Agrochemical Industry:
In the agrochemical sector, 2-Thiophenecarboxylic acid, ion(1-) is utilized as a building block for the creation of novel agrochemicals. Its reactivity and properties make it suitable for the development of new pesticides, herbicides, and other agricultural chemicals to enhance crop protection and yield.
Used in Organic Compounds Synthesis:
2-Thiophenecarboxylic acid, ion(1-) is used as a versatile precursor in the synthesis of a wide range of organic compounds. Its unique structure and reactivity contribute to the development of new materials and compounds for various applications across different industries.
Check Digit Verification of cas no
The CAS Registry Mumber 20897-85-2 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 2,0,8,9 and 7 respectively; the second part has 2 digits, 8 and 5 respectively.
Calculate Digit Verification of CAS Registry Number 20897-85:
(7*2)+(6*0)+(5*8)+(4*9)+(3*7)+(2*8)+(1*5)=132
132 % 10 = 2
So 20897-85-2 is a valid CAS Registry Number.
20897-85-2Relevant articles and documents
Enhanced reactivity of twisted amides inside a molecular cage
Takezawa, Hiroki,Shitozawa, Kosuke,Fujita, Makoto
, p. 574 - 578 (2020/05/05)
When an amide group is distorted from its planar conformation, the conjugation between the nitrogen lone pair and the π* orbital of the carbonyl is disrupted and the reactivity towards nucleophiles is enhanced. Although there are several reports on the synthesis of activated twisted amides, amide activation through mechanical twisting is much less common. Here, we report twisted amides that are stabilized through their inclusion in a self-assembled coordination cage. When secondary aromatic amides are included in a Td-symmetric cage, the cis-twisted conformation is favoured over the trans-planar one—as evidenced by single-crystal X-ray diffraction analysis—revealing that the amide can twist by up to 34°. As a consequence of this distortion, the hydrolysis of amides is significantly accelerated upon inclusion. [Figure not available: see fulltext.]
