209481-20-9 Usage
General Description
SB271046 is a potent and selective antagonist of the 5-HT6 receptor, a subtype of serotonin receptor. It has been used in research to investigate the role of the 5-HT6 receptor in various cognitive and neurological disorders, such as schizophrenia and Alzheimer's disease. SB271046 has been shown to have potential therapeutic effects in preclinical studies, including enhancing memory and cognitive function, and is therefore a promising candidate for the development of novel treatments for conditions involving cognitive impairment. Additionally, it has also been studied for its potential in treating substance abuse disorders and obesity. Overall, SB271046 is a valuable tool in understanding the function of the 5-HT6 receptor and has potential implications for the development of novel therapeutics in the field of neuroscience and neuropsychiatry.
Check Digit Verification of cas no
The CAS Registry Mumber 209481-20-9 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 2,0,9,4,8 and 1 respectively; the second part has 2 digits, 2 and 0 respectively.
Calculate Digit Verification of CAS Registry Number 209481-20:
(8*2)+(7*0)+(6*9)+(5*4)+(4*8)+(3*1)+(2*2)+(1*0)=129
129 % 10 = 9
So 209481-20-9 is a valid CAS Registry Number.
209481-20-9Relevant articles and documents
Sulphonamide derivatives, process for their preparation, and their use as medicaments
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, (2008/06/13)
Novel sulphonamide derivatives having CNS activity, processes for their preparation and their use as medicaments are disclosed. The present compounds are of formula (I) or a salt thereof: wherein: P isbenzothiophene, benzothiadiazole, quinoline, benzofuran or indole; A is a single bond, a C1-6alkylene or a C1-6alkenylene group; R1is halogen, C1-6alkyl optionally substituted by one or more halogen atoms, C3-6cycloalkyl, COC1-6alkyl, C1-6alkoxy, OCF3, hydroxy, hydroxyC1-6alkyl, hydroxyC1-6alkoxy, C1-6alkoxyC1-6alkoxy, nitro, amino, C1-6alkylamino or C1-6dialkylamino, cyano or R1is phenyl or naphthyl; n is 0, 1, 2, 3, 4, 5, or 6; R2is hydrogen, C1-6alkyl or aryl C1-6alkyl or R2is linked to R3to form a group (CH2)2or (CH2)3; R3is a group R5or together with R5forms a group (CH2)2O or (CH2)3O or R3is linked to R2to form a group (CH2)2or (CH2)3; R4is an N-piperazine ring optionally substituted by C1-6alkyl; and R5is hydrogen, halogen, C1-6alkyl, C3-6cycloalkyl, COC1-6alkyl, C1-6alkoxy, hydroxy, hydroxyC1-6alkyl, hydroxyC1-6alkoxy, C1-6alkoxyC1-6alkoxy, nitro, trifluoromethyl, cyano or aryl.