2095-62-7 Usage
Description
7-Hydroxychlorpromazine, also known as 7-hydroxy-2-chloropromazine, is a significant metabolite of the atypical antipsychotic drug Chlorpromazine. It possesses various pharmacological properties, including antiadrenergic, antiserotonergic, anticholinergic, and antihistaminergic activities, which contribute to its therapeutic effects.
Uses
Used in Pharmaceutical Industry:
7-Hydroxychlorpromazine is used as an active metabolite for enhancing the therapeutic effects of Chlorpromazine in the treatment of schizophrenia. Its presence in the body helps to improve the overall efficacy of the antipsychotic medication by contributing to the modulation of various neurotransmitter systems involved in the disorder.
Used in Research and Development:
7-Hydroxychlorpromazine is utilized as a research compound for studying the pharmacological properties and mechanisms of action of Chlorpromazine. This helps in understanding the drug's effects on different neurotransmitter systems and its role in the treatment of schizophrenia and other related conditions.
Used in Drug Metabolism Studies:
7-Hydroxychlorpromazine serves as a key metabolite in the study of drug metabolism and pharmacokinetics of Chlorpromazine. Understanding its formation, distribution, and elimination in the body can provide valuable insights into the drug's safety, efficacy, and potential drug-drug interactions.
Check Digit Verification of cas no
The CAS Registry Mumber 2095-62-7 includes 7 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 4 digits, 2,0,9 and 5 respectively; the second part has 2 digits, 6 and 2 respectively.
Calculate Digit Verification of CAS Registry Number 2095-62:
(6*2)+(5*0)+(4*9)+(3*5)+(2*6)+(1*2)=77
77 % 10 = 7
So 2095-62-7 is a valid CAS Registry Number.
InChI:InChI=1/C17H19ClN2OS/c1-19(2)8-3-9-20-14-6-5-13(21)11-17(14)22-16-7-4-12(18)10-15(16)20/h4-7,10-11,21H,3,8-9H2,1-2H3
2095-62-7Relevant articles and documents
Bacterial Biosynthetic P450 Enzyme PikCD50N: A Potential Biocatalyst for the Preparation of Human Drug Metabolites
Cheng, Fangyuan,Du, Lei,Durairaj, Pradeepraj,Guo, Jiawei,Li, Fengwei,Li, Shengying,Liu, Xiaohui,Long, Xiangtian,Ma, Li,Tang, Dandan,Zhang, Gang,Zhang, Wei,Zhang, Xingwang
, p. 14563 - 14571 (2021/11/12)
Human drug metabolites (HDMs) are important chemicals widely used in drug-related studies. However, acquiring these enzyme-derived and regio-/stereo-selectively modified compounds through chemical approaches is complicated. PikC is a biosynthetic P450 enz
