20963-97-7

Basic information

• Product Name: Cytidine, 2'-deoxy-, 3',5'-dibenzoate
• Synonyms: O3',O5'-dibenzoyl-2'-deoxy-cytidine;3',5'-O-O-Dibenzoyldeoxycytidine;3',5'-Di-O-benzoyl-desoxycytidin
• CAS NO: 20963-97-7
• Molecular Formula: C23H21N3O6
• Molecular Weight: 435.436
• Mol File: 20963-97-7.mol
• Article Data: 6

Chemical Properties

• Melting Point: 202-205 °C
• Boiling Point: 614.9±65.0 °C(Predicted)
• Density: 1.39±0.1 g/cm3(Predicted)
• CAS DataBase Reference: Cytidine, 2'-deoxy-, 3',5'-dibenzoate(CAS DataBase Reference)
• NIST Chemistry Reference: Cytidine, 2'-deoxy-, 3',5'-dibenzoate(20963-97-7)
• EPA Substance Registry System: Cytidine, 2'-deoxy-, 3',5'-dibenzoate(20963-97-7)

Safety Data

• Hazardous Substances Data: 20963-97-7(Hazardous Substances Data)

Upstream product

• 18037-10-0 2,4-O,N-bis(trimethylsilyl)cytosine 
• 175024-33-6 C₂₃H₂₉N₂O₇P 
• 51255-12-0 1-O-acetyl-3,5-di-O-benzoyl-2-deoxy-D-erythro-pentafuranose 
• 67014-25-9 bis(trimethylsilyl)cytosine 
• 613-90-1 benzoyl cyanide 
• 951-77-9 2'-Deoxycytidine 
• 31501-22-1 N⁴-benzoyl-1-(3',5'-di-O-benzoyl-2'-deoxy-β-D-ribofuranosyl)-cytosine 

Downstream Products

• 4449-40-5 α-2'-deoxycytidine 
• 951-77-9 2'-Deoxycytidine 

Relevant articles and documents

'Green' methodology for efficient and selective benzoylation of nucleosides using benzoyl cyanide in an ionic liquid

Benzoyl cyanide in the ionic liquid 1-methoxyethyl-3-methylimidazolium methanesulfonate has been employed as a 'green' alternative and mild reaction condition protocol to conventional pyridine-benzoyl chloride system for efficient and selective benzoylation of nucleosides (of both the ribo- and deoxyribo-series) at ambient temperatures. The use of benzoyl cyanide-ionic liquid combination has been successfully extended for highly efficient benzoylation of phenols, aromatic amines, benzyl alcohol, aliphatic diols, 3-aminophenol and 2-aminobenzylalcohol, which indicates the versatility of this benzoylating system.

Mild, efficient, selective and "green" benzoylation of nucleosides using benzoyl cyanide in ionic liquid

Use of benzoyl cyanide (BzCN) for benzoylation of nucleosides has been studied, both in pyridine and in ionic liquid. BzCN in 1-methoxyethyl-3- methylimidazolium methanesulfonate as ionic liquid has been found to be a "green" alternative compared to the pyridine-BzCN system. An efficient and selective benzoylation of nucleosides of both, the 2′-deoxy- and the ribo-series at ambient temperature was accomplished. Copyright Taylor & Francis, Inc.

Improved procedure for the regiospecific synthesis of 2'-deoxyribonucleosides

2'-Deoxyribonucleosides are regiospecifically synthesized in high yields by catalyzing with KI-dibenzo-18-crown-6 PTC the condensation between unprotected silylated purines and pyrimidines and the appropriate easily available 2-deoxy-ribofuranosyl or pyranosyl sugar derivatives.