209685-47-2

Basic information

• Product Name: methyl 4-({2-[(phenylsulfonyl)amino]-5-(trifluoromethyl)phenoxy}methyl)benzoate
• Synonyms: methyl 4-({2-[(phenylsulfonyl)amino]-5-(trifluoromethyl)phenoxy}methyl)benzoate
• CAS NO: 209685-47-2
• Molecular Weight: 465.45
• Mol File: 209685-47-2.mol
• Article Data: 3

Chemical Properties

• CAS DataBase Reference: methyl 4-({2-[(phenylsulfonyl)amino]-5-(trifluoromethyl)phenoxy}methyl)benzoate(CAS DataBase Reference)
• NIST Chemistry Reference: methyl 4-({2-[(phenylsulfonyl)amino]-5-(trifluoromethyl)phenoxy}methyl)benzoate(209685-47-2)
• EPA Substance Registry System: methyl 4-({2-[(phenylsulfonyl)amino]-5-(trifluoromethyl)phenoxy}methyl)benzoate(209685-47-2)

Safety Data

• Hazardous Substances Data: 209685-47-2(Hazardous Substances Data)

Upstream product

• 907587-49-9 methyl 4-[(2-amino-5-(trifluoromethyl)phenoxy)methyl]benzoate 
• 98-09-9 benzenesulfonyl chloride 
• 2417-72-3 Methyl 4-(bromomethyl)benzoate 
• 402-17-5 2-nitro-5-trifluoromethylphenol 
• 402-54-0 p-nitrobenzotrifluoride 
• 907587-46-6 methyl 4-[(2-nitro-5-(trifluoromethyl)phenoxy)methyl]benzoate 

Downstream Products

• 907587-57-9 methyl 4-{[2-[(phenylsulfonyl)(propyl)amino]-5-(trifluoromethyl)phenoxy]methyl}benzoate 
• 907587-56-8 methyl 4-{[2-[ethyl(phenylsulfonyl)amino]-5-(trifluoromethyl)phenoxy]methyl}benzoate 
• 907587-58-0 methyl 4-{[2-[isobutyl(phenylsulfonyl)amino]-5-(trifluoromethyl)phenoxy]methyl}benzoate 
• 907587-59-1 methyl 4-{[2-[neopentyl(phenylsulfonyl)amino]-5-(trifluoromethyl)phenoxy]methyl}benzoate 
• 209686-79-3 methyl 4-{[2-[(cyclopentylmethyl)(phenylsulfonyl)amino]-5-(trifluoromethyl)phenoxy]methyl}benzoate 

Relevant articles and documents

Discovery of new chemical leads for selective EP1 receptor antagonists

A series of 4-({2-[alkyl(phenylsulfonyl)amino]phenoxy}methyl)benzoic acids were identified as functional PGE2 antagonists with selectivity for the EP1 receptor subtype starting from a chemical lead 1, which was found while screening our in-house compound library. Discovery of the optimized analogs 21-23 is presented here and structure-activity relationships (SAR) are also discussed.

Sulfonamide and carboxamide derivatives and drugs containing the same as the active ingredient

The sulfonamide or carboamide derivatives of the formula (I) and a pharmaceutical composition which comprise them as an active ingredient: (wherein A ring, B ring is carbocyclic ring, heterocyclic ring; Z1is —COR1, —CH═CH—COR1/