2098-65-9

Basic information

• Product Name: 17α-hydroxy-1α,2α-methylene-4,6-pregnadiene-3,20-dione
• Synonyms: 17α-hydroxy-1α,2α-methylene-4,6-pregnadiene-3,20-dione
• CAS NO: 2098-65-9
• Molecular Weight: 340.463
• Mol File: 2098-65-9.mol
• Article Data: 3

Chemical Properties

• CAS DataBase Reference: 17α-hydroxy-1α,2α-methylene-4,6-pregnadiene-3,20-dione(CAS DataBase Reference)
• NIST Chemistry Reference: 17α-hydroxy-1α,2α-methylene-4,6-pregnadiene-3,20-dione(2098-65-9)
• EPA Substance Registry System: 17α-hydroxy-1α,2α-methylene-4,6-pregnadiene-3,20-dione(2098-65-9)

Safety Data

• Hazardous Substances Data: 2098-65-9(Hazardous Substances Data)

Usage

Uses

3''H-Cyclopropa[1,2]cyclopenta[a]phenanthrene is a water soluble gestational steroid.

Upstream product

• 66212-25-7 1,4,6-triene-3,20-dione-17α-hydroxyprogesterone 
• 25596-24-1 trimethyloxosulfonium bromide 

Downstream Products

• 2701-50-0 1,2α-methylene-Δ4,6-pregnadiene-17α-ol-3,20-dione-17-acetate 
• 17183-98-1 6-chloro-1α-chloromethyl-Δ4,6-pregnadien-17α-ol-3,20-dione-17-acetate 
• 427-51-0 cyproterone acetate 
• 15423-97-9 1,2α-methylene-6,7α-oxido-Δ4-pregnen-17α-ol-3,20-dione-17-acetate 

Relevant articles and documents

Production technology and production device of c`yproterone acetate

The invention discloses a cyproterone acetate production device. The cyproterone acetate production device comprises a reaction kettle, an elutriation kettle, a centrifugal machine, a concentration kettle, a decoloration kettle and a drying device, wherein the drying device comprises an outer cylinder, a drying cylinder and an inner cylinder; a motor is arranged on the bottom surface of the outercylinder; exhausting fan blades, cylinder type impellers and vortex impellers are arranged on a rotating shaft of the motor; the exhausting fan blades are arranged between the drying cylinder and thebottom surface of the outer barrel; the cylinder type impellers are arranged between the drying cylinder and the inner cylinder; the vortex impellers are arranged at the bottom of the inner cylinder;an infrared ray heating pipe is arranged on the top surface of the inner cylinder; a rotating air purifying ring is arranged at the upper end of a sandwiching chamber of the outer cylinder; a mountingring is arranged on a top plate, and a gear ring is arranged in the mounting ring; screw rods and slide bars are arranged at the bottom of the mounting ring annularly and evenly in a staggering manner; pinions are arranged on the tops of the screw rods and are meshed with the gear ring; one of the screw rods is connected to an operating crank; a turnover cover is arranged on the top end of the mounting ring; and a tray is arranged on the screw rods. The cyproterone acetate production device can reduce the preparation time of intermediate products in the production process of cyproterone acetate, and realizes the rapid high-quality production of the cyproterone acetate.

Combined antiestrogens and antigonadotropically effective antiandrogens for the prophylaxis and therapy of hyperplasia of the prostate

A pharmaceutical composition comprising an anti-estrogen and an antigonadotropically effective anti-androgen, e.g., in a weight ratio of anti-estrogen to anti-androgen of essentially 2:1 to 1:10 is effective for the prophylaxis and therapy of prostate hyperplasia. Suitable anti-estrogens include, for example, tamoxifen. Antigonadotropically active anti-androgens preferably are steroids having anti-androgenic and progestational properties, e.g., cyproterone acetate.