21002-15-3

Basic information

• Product Name: 1,3,5-Triazine, 2,4-dimethoxy-6-phenoxy-
• CAS NO: 21002-15-3
• Molecular Formula: C11H11N3O3
• Molecular Weight: 233.227
• Mol File: 21002-15-3.mol
• Article Data: 3

Chemical Properties

• CAS DataBase Reference: 1,3,5-Triazine, 2,4-dimethoxy-6-phenoxy-(CAS DataBase Reference)
• NIST Chemistry Reference: 1,3,5-Triazine, 2,4-dimethoxy-6-phenoxy-(21002-15-3)
• EPA Substance Registry System: 1,3,5-Triazine, 2,4-dimethoxy-6-phenoxy-(21002-15-3)

Safety Data

• Hazardous Substances Data: 21002-15-3(Hazardous Substances Data)

Upstream product

• 3140-73-6 2-chloro-4,6-dimethoxy-1 ,3,5-triazine 
• 108-95-2 phenol 
• 163684-97-7 4-(3',4'-dinitrophenoxy)-2,6-dimethoxy-1,3,5-trazine 
• 163685-00-5 2-(3,5-Dinitro-phenoxy)-4,6-dimethoxy-[1,3,5]triazine 
• 163685-03-8 2-(2-Chloro-4-nitro-phenoxy)-4,6-dimethoxy-[1,3,5]triazine 
• 163685-01-6 2-(3-Chloro-4-nitro-phenoxy)-4,6-dimethoxy-[1,3,5]triazine 
• 163685-02-7 2-(4-Chloro-3-nitro-phenoxy)-4,6-dimethoxy-[1,3,5]triazine 
• 163684-98-8 2,4-Dimethoxy-6-(3-nitro-phenoxy)-[1,3,5]triazine 
• 163684-99-9 3-(4,6-Dimethoxy-[1,3,5]triazin-2-yloxy)-benzaldehyde 
• 28690-95-1 2-(4-nitrophenoxy)-4,6-dimethoxy-1,3,5-triazine 
• 42030-76-2 4-((4,6-dimethoxy-1,3,5-triazin-2-yl)oxy)benzaldehyde 
• 3229-70-7 phenolate 

Downstream Products

• 613-37-6 4-methoxylbiphenyl 
• 1759-68-8 N-benzoylcyclohexylamine 
• 100-47-0 benzonitrile 

Relevant articles and documents

Nickel-catalyzed Suzuki-Miyaura coupling of heteroaryl ethers with arylboronic acids

Nickel-catalyzed Suzuki-Miyaura coupling of heteroaryl ethers with arylboronic acids was described. Selective activation of the phenol C-O bonds was achieved by converting them into the corresponding aryl 2,4-dimethoxy-1,3,5- triazine-6-yl ethers, in which aryl C-O bond could be selectively cleaved with inexpensive, air-stable NiCl2(dppf) as a catalyst. Coupling of these readily accessible heteroaryl ethers proved tolerant of extensive functional groups.

A Single Transition State in Nucleophilic Aromatic Substitution: Reaction of Phenolate Ions with 2-(4-Nitrophenoxy)-4,6-dimethoxy-1,3,5-triazine in Aqueous Solution

The absence of curvature in the Broensted dependence for displacement of 4-nitrophenolate ion from the title ether by phenolate ion nucleophiles with pKas well below and above that of the leaving group is consistent with a single step mechanism.