21003-63-4

Basic information

• Product Name: (R)-1,2,2,2-tetraphenyl-ethanol
• Synonyms: (R)-1,2,2,2-tetraphenyl-ethanol
• CAS NO: 21003-63-4
• Molecular Weight: 350.46
• Mol File: 21003-63-4.mol
• Article Data: 4

Chemical Properties

• CAS DataBase Reference: (R)-1,2,2,2-tetraphenyl-ethanol(CAS DataBase Reference)
• NIST Chemistry Reference: (R)-1,2,2,2-tetraphenyl-ethanol(21003-63-4)
• EPA Substance Registry System: (R)-1,2,2,2-tetraphenyl-ethanol(21003-63-4)

Safety Data

• Hazardous Substances Data: 21003-63-4(Hazardous Substances Data)

Upstream product

• 466-37-5 benzopinacolone 
• 18026-23-8 1,2,2,2-tetraphenylethanol 
• 116378-54-2 ((1R)-menthyloxy)-acetic acid-((R)-1,2,2,2-tetraphenyl-ethyl ester) 

Relevant articles and documents

Enantioseparation on Riboflavin Derivatives Chemically Bonded to Silica Gel as Chiral Stationary Phases for HPLC

Acetylated and/or 3,5-dimethylphenylcarbamated riboflavins were prepared and the resulting riboflavin derivatives as well as natural riboflavin were regioselectively immobilized on silica gel through chemical bonding at the 5'-O- or 3-N-position of the riboflavin to develop novel chiral stationary phases (CSPs) for enantioseparation by high-performance liquid chromatography (HPLC). The chiral recognition abilities of the obtained CSPs were significantly dependent on the structures of the riboflavin derivatives, the position of the chemical bonding on the silica gel, and the structures of the racemic compounds. The CSPs bonded at the 5'-O-position on the silica gel tended to well separate helicene derivatives, while the CSPs bonded at the 3-N-position composed of acetylated and 3,5-dimethylphenylcarbamated riboflavins showed a better resolving ability toward helicene derivatives and bulky aromatic racemic alcohols, respectively, and some of them were completely separated into the enantiomers. The observed difference in the chiral recognition abilities of these riboflavin-based CSPs is discussed based on the difference in their structures, including the substituents of riboflavin and the positions immobilized on the silica gel. Chirality 27:507-517, 2015.

SEPARATING AGENT FOR OPTICAL ISOMER AND METHOD FOR PREPARATION THEREOF

To provide a separating agent which combines a high optical resolving power inherent in polysaccharide derivatives with sufficient solvent resistance and a method with which the separating agent can be produced efficiently in short steps. The separating agent for enantiomeric isomers is characterized in that a polymerizable polysaccharide derivative of a polysaccharide derivative having polymerizable functional groups and a polymerizable monomer having polymerizable unsaturated groups are copolymerized with a carrier having polymerizable functional groups to be chemically bound mutually. The separating agent is preferably used for high performance liquid chromatography (HPLC), and is excellent in solvent resistance.