210035-01-1

Basic information

• Product Name: (2,6-Dichloro-phenyl)-imidazo[1,5-a]pyridin-1-yl-methanone
• Synonyms: (2,6-Dichloro-phenyl)-imidazo[1,5-a]pyridin-1-yl-methanone
• CAS NO: 210035-01-1
• Molecular Weight: 291.136
• Mol File: 210035-01-1.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: (2,6-Dichloro-phenyl)-imidazo[1,5-a]pyridin-1-yl-methanone(CAS DataBase Reference)
• NIST Chemistry Reference: (2,6-Dichloro-phenyl)-imidazo[1,5-a]pyridin-1-yl-methanone(210035-01-1)
• EPA Substance Registry System: (2,6-Dichloro-phenyl)-imidazo[1,5-a]pyridin-1-yl-methanone(210035-01-1)

Safety Data

• Hazardous Substances Data: 210035-01-1(Hazardous Substances Data)

Upstream product

• 274-47-5 imidazo[1,5-a]pyridine 
• 4659-45-4 2,6-Dichlorobenzoyl chloride 

Downstream Products

• 210035-04-4 1-(2,6-Dichloro-benzyl)-imidazo[1,5-a]pyridine 
• 210035-06-6 (2,6-Dichloro-phenyl)-imidazo[1,5-a]pyridin-1-yl-methanol 

Relevant articles and documents

The regioselective acylation reactions of imidazopyridines

The regioselectivity of acylation in imidazopyridines can be controlled by two mechanism-specific reactions. As expected acylation reactions under Friedel-Crafts conditions result in reaction at the most electron-rich site in imidazopyridines. However, depending on the structure of the imidazopyridine, ylid intermediates are proposed to direct reaction to the electron-deficient site in the parent heterocycles. These observations led to the selective synthesis of acylimidazopyridines and this methodology was used in the preparation of analogs of the α2-adrenergic agonists MPV-207 and clonidine. 1. This research was conducted at Sterling Winthrop Pharmaceuticals Research Division prior to its acquisition by Sanofi, Inc.