21028-13-7

Basic information

• Product Name: (R)-(+)-2-hydrazinopropionic acid
• Synonyms: (R)-(+)-2-hydrazinopropionic acid
• CAS NO: 21028-13-7
• Molecular Weight: 104.109
• Mol File: 21028-13-7.mol
• Article Data: 3

Chemical Properties

• CAS DataBase Reference: (R)-(+)-2-hydrazinopropionic acid(CAS DataBase Reference)
• NIST Chemistry Reference: (R)-(+)-2-hydrazinopropionic acid(21028-13-7)
• EPA Substance Registry System: (R)-(+)-2-hydrazinopropionic acid(21028-13-7)

Safety Data

• Hazardous Substances Data: 21028-13-7(Hazardous Substances Data)

Upstream product

• 103836-65-3 C₂₄H₃₉N₃O₆ 
• 54600-98-5 N^α,N^β-Di(benzyloxycarbonyl)-DL-α-hydrazinopropionsaeure 
• 142068-29-9 ethyl pyruvate benzoylhydrazone 
• 32644-15-8 (S)-2-bromopropanoic acid 

Downstream Products

• 338-69-2 D-Alanine 

Relevant articles and documents

Catalytic asymmetric reductive amination of ketones via highly enantioselective hydrogenation of the C=N double bond

We describe a convenient, chemoselective asymmetric reductive amination procedure for the conversion of ketones to chiral hydrazines and amines. The key step in the three-step process is enantioselective DuPHOS-Rh-catalyzed hydrogenation of the C=N double bond of N-acylhydrazones. Detailed optimization studies revealed the effect of solvent, temperature, and the N- acyl group on the enantioselectivity and catalytic efficiency of the reaction. The reduction products, N-acylhydrazines, were converted to hydrazines or amines through hydrolysis or treatment with samarium(II) iodide, respectively.

Asymmetric Electrophilic Amination: Synthesis of α-Amino and α-Hydrazino Acids with High Optical Purity

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